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L3MBTL2 gene

Known as: l(3)mbt-like 2 (Drosophila), H-l(3)mbt-l, L3MBT, DROSOPHILA, HOMOLOG OF, 2 
 
National Institutes of Health

Related topics

Related topics

2 relations
L3MBTL2 protein, humanL3MBTL3 gene

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
L3MBTL2 orchestrates ubiquitin signaling by dictating the sequential recruitment of RNF8 and RNF168 after DNA damage
Cells respond to cytotoxic DNA double-strand breaks (DSBs) by recruiting DNA repair proteins to the damaged site. This… Expand
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2018
2018
MGA, L3MBTL2 and E2F6 determine genomic binding of the non-canonical Polycomb repressive complex PRC1.6
Diverse Polycomb repressive complexes 1 (PRC1) play essential roles in gene regulation, differentiation and development. Six… Expand
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2018
2018
Combinatorial Control of Recruitment of a Variant PRC1.6 Complex in Embryonic Stem Cells.
Though genetic data suggest that Polycomb group proteins (PcGs) are central chromatin modifiers and repressors that have been… Expand
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2018
2018
The GWAS Risk Genes for Depression May Be Actively Involved in Alzheimer's Disease.
Depression is one of the most frequent psychiatric symptoms observed in people during the development of Alzheimer's disease (AD… Expand
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2018
2018
Calling RNF168 to action
Genomic stress leads to various forms of DNA damage, of which DNA double strand breaks (DSBs) are the most lethal. An army of… Expand
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2017
2017
Genome-wide analyses for personality traits identify six genomic loci and show correlations with psychiatric disorders
Personality is influenced by genetic and environmental factors and associated with mental health. However, the underlying genetic… Expand
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Highly Cited
2012
Highly Cited
2012
The polycomb group protein L3mbtl2 assembles an atypical PRC1-family complex that is essential in pluripotent stem cells and early development.
L3mbtl2 has been implicated in transcriptional repression and chromatin compaction but its biological function has not been… Expand
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Highly Cited
2011
Highly Cited
2011
L3MBTL2 protein acts in concert with PcG protein-mediated monoubiquitination of H2A to establish a repressive chromatin structure.
We have identified human MBT domain-containing protein L3MBTL2 as an integral component of a protein complex that we termed… Expand
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2009
2009
Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2
The MBT repeat has been recently identified as a key domain capable of methyl-lysine histone recognition. Functional work has… Expand
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2009
2009
Structural Studies of a Four-MBT Repeat Protein MBTD1
BACKGROUND The Polycomb group (PcG) of proteins is a family of important developmental regulators. The respective members… Expand
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