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L-NDDP
Known as:
Liposomal Neodecanoic Acid Platinum Complex
, Liposomal-Entrapped Cis-Bis-Neodecanoate-trans-R,R-1,2-Diaminocyclohexane Platinum (II)
, liposomal-NDDP
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A synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation platinum complex analogue of cisplatin…
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National Institutes of Health
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Related topics
Related topics
5 relations
DNA
DNA Crosslinking
DNA Synthesis Inhibition
RNA Transcription Inhibition
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Neoadjuvant and intrapleural therapies for malignant pleural mesothelioma.
A. Tsao
,
R. Mehran
,
J. Roth
Clinical Lung Cancer
2009
Corpus ID: 11633051
Historically, malignant pleural mesothelioma patients with potentially resectable disease have been treated with surgery and…
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Review
2007
Review
2007
Broadening the clinical use of platinum drug–based chemotherapy with new analogues
L. Kèlland
Expert Opinion on Investigational Drugs
2007
Corpus ID: 44788228
The three platinum-containing drugs that have been thus far approved by the FDA – cisplatin, carboplatin and oxaliplatin – have…
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Highly Cited
2006
Highly Cited
2006
A Phase 2 trial of the liposomal DACH platinum L-NDDP in patients with therapy-refractory advanced colorectal cancer
T. Dragovich
,
D. Mendelson
,
S. Kurtin
,
K. Richardson
,
D. V. Hoff
,
A. Hoos
Cancer Chemotherapy and Pharmacology
2006
Corpus ID: 26078809
Purpose: L-NDDP (AroplatinTM) is a liposomal formulation of cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II…
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Highly Cited
2005
Highly Cited
2005
Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma.
Charles Lu
,
R. Perez-soler
,
+12 authors
D. Shin
Journal of Clinical Oncology
2005
Corpus ID: 43081414
PURPOSE To determine pathologic response rates to liposome-entrapped cis-bisneodecanoato-trans-R,R-1,2-diaminocyclohexane…
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2001
2001
A high-throughput screen for identifying transmembrane pore-forming peptides.
J. M. Rausch
,
W. Wimley
Analytical Biochemistry
2001
Corpus ID: 2614802
We have developed a visual microwell plate assay for rapid, high-throughput screening for membrane-disrupting molecules such as…
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1997
1997
Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions.
R. Perez-soler
,
D. Shin
,
+5 authors
W. Hong
Clinical Cancer Research
1997
Corpus ID: 14649870
cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II) (NDDP) is a lipophilic non-cross-resistant platinum compound…
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1996
1996
Preparation and characterization of poly-(D,L-lactide-co-glycolide) and poly-(L-lactic acid) microspheres with entrapped pneumotropic bacterial antigens.
N. Kofler
,
C. Ruedl
,
+4 authors
H. Wolf
JIM - Journal of Immunological Methods
1996
Corpus ID: 45779672
Review
1993
Review
1993
New Cisplatin Analogues in Development
R. Weiss
,
M. Christian
Drugs
1993
Corpus ID: 25220681
SummaryCisplatin was discovered to have cytotoxic properties in the 1960s, and by the end of the 1970s it had earned a place as…
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1990
1990
Topical liposomal delivery of antibiotics in soft tissue infection.
C. Price
,
J. Horton
,
C. Baxter
Journal of Surgical Research
1990
Corpus ID: 39776853
Highly Cited
1990
Highly Cited
1990
Phase I clinical and pharmacological study of liposome-entrapped cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II).
R. Perez-soler
,
G. Lopez-Berestein
,
+5 authors
A. Khokhar
Cancer Research
1990
Corpus ID: 19518910
cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum++ +(II) (NDDP) is a liposome dependent cisplatin analogue since the…
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