Skip to search formSkip to main contentSkip to account menu

L-NDDP

Known as: Liposomal Neodecanoic Acid Platinum Complex, Liposomal-Entrapped Cis-Bis-Neodecanoate-trans-R,R-1,2-Diaminocyclohexane Platinum (II), liposomal-NDDP 
A synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation platinum complex analogue of cisplatin… 
National Institutes of Health

Related topics

Related topics

5 relations
DNADNA CrosslinkingDNA Synthesis InhibitionRNA Transcription Inhibition

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2009
Review
2009
Neoadjuvant and intrapleural therapies for malignant pleural mesothelioma.
Historically, malignant pleural mesothelioma patients with potentially resectable disease have been treated with surgery and… 
Review
2007
Review
2007
Broadening the clinical use of platinum drug–based chemotherapy with new analogues
  • L. Kèlland
  • Expert Opinion on Investigational Drugs
  • 2007
  • Corpus ID: 44788228
The three platinum-containing drugs that have been thus far approved by the FDA – cisplatin, carboplatin and oxaliplatin – have… 
Highly Cited
2006
Highly Cited
2006
A Phase 2 trial of the liposomal DACH platinum L-NDDP in patients with therapy-refractory advanced colorectal cancer
Purpose: L-NDDP (AroplatinTM) is a liposomal formulation of cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II… 
Highly Cited
2005
Highly Cited
2005
Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma.
PURPOSE To determine pathologic response rates to liposome-entrapped cis-bisneodecanoato-trans-R,R-1,2-diaminocyclohexane… 
2001
2001
A high-throughput screen for identifying transmembrane pore-forming peptides.
We have developed a visual microwell plate assay for rapid, high-throughput screening for membrane-disrupting molecules such as… 
1997
1997
Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions.
cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II) (NDDP) is a lipophilic non-cross-resistant platinum compound… 
1996
1996
Preparation and characterization of poly-(D,L-lactide-co-glycolide) and poly-(L-lactic acid) microspheres with entrapped pneumotropic bacterial antigens.
Review
1993
Review
1993
New Cisplatin Analogues in Development
SummaryCisplatin was discovered to have cytotoxic properties in the 1960s, and by the end of the 1970s it had earned a place as… 
1990
1990
Topical liposomal delivery of antibiotics in soft tissue infection.
Highly Cited
1990
Highly Cited
1990
Phase I clinical and pharmacological study of liposome-entrapped cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II).
cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexaneplatinum++ +(II) (NDDP) is a liposome dependent cisplatin analogue since the… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)