FAQ

L-NDDP

Known as: Liposomal Neodecanoic Acid Platinum Complex, Liposomal-Entrapped Cis-Bis-Neodecanoate-trans-R,R-1,2-Diaminocyclohexane Platinum (II), liposomal-NDDP 
A synthetic liposomal formulation of bis-neodecanoate diaminocyclohexane platinum (NDDP), a third-generation platinum complex analogue of cisplatin… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1986-2016
02419862016

Related topics

Related topics

5 relations
DNADNA CrosslinkingDNA Synthesis InhibitionRNA Transcription Inhibition
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Related mentions per year

Related mentions per year

1945-2018
19401960198020002020
L-NDDP
DNA
DNA Synthesis Inhibition
DNA Crosslinking
liposomal oxaliplatin
RNA Transcription Inhibition

Papers overview

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2012
2012
Drug Release Patterns and Cytotoxicity of PEG-poly(aspartate) Block Copolymer Micelles in Cancer Cells
To test physicochemical and biological properties of PEG-poly(aspartate) [PEG-p(Asp)] block copolymer micelles entrapping… (More)
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2010
2010
Transcription inhibition by platinum-DNA cross-links in live mammalian cells.
We have investigated the processing of site-specific Pt-DNA cross-links in live mammalian cells to enhance our understanding of… (More)
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2009
2009
Cell-responsive hydrogel for encapsulation of vascular cells.
The in vitro potential of a synthetic matrix metalloproteinase (MMP)-responsive poly(ethylene glycol) (PEG)-based hydrogel as a… (More)
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2009
2009
Long-term reduction of jaundice in Gunn rats by nonviral liver-targeted delivery of Sleeping Beauty transposon.
UNLABELLED Asialoglycoprotein receptor (ASGPR)-mediated endocytosis has been used to target genes to hepatocytes in vivo. However… (More)
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2006
2006
A Phase 2 trial of the liposomal DACH platinum L-NDDP in patients with therapy-refractory advanced colorectal cancer
Purpose: L-NDDP (AroplatinTM) is a liposomal formulation of cis-bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum (II… (More)
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2006
2006
Paradoxical and pulmonary embolism due to a thrombus entrapped in a patent foramen ovale.
A 70-year-old woman, with a history of recent thromboembolic stroke, was admitted to our hospital because of sudden dyspnea due… (More)
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2005
2005
Phase II study of a liposome-entrapped cisplatin analog (L-NDDP) administered intrapleurally and pathologic response rates in patients with malignant pleural mesothelioma.
PURPOSE To determine pathologic response rates to liposome-entrapped cis-bisneodecanoato-trans-R,R-1,2-diaminocyclohexane… (More)
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1997
1997
Phase I clinical and pharmacological study of liposome-entrapped NDDP administered intrapleurally in patients with malignant pleural effusions.
cis-Bis-neodecanoato-trans-R,R-1,2-diaminocyclohexane platinum(II) (NDDP) is a lipophilic non-cross-resistant platinum compound… (More)
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1991
1991
Efficiency of liposomal ATP in cerebral ischemia: bioavailability features.
This study was performed to elucidate the mechanism by which adenosine triphosphate (ATP) encapsulated into liposomes was able to… (More)
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1987
1987
Ultrastructural and freeze fracture localization of multilamellar liposomes containing a lipophilic cisplatin analogue in normal tissues and liver metastases of M5076 reticulosarcoma.
The tissue localization of multilamellar vesicles (MLV) (size 0.5-5.0 microns) composed of dimyristoylphosphatidyl choline (DMPC… (More)
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