Skip to search formSkip to main contentSkip to account menu

DNA Crosslinking

Known as: DNA Crosslink 
DNA Crosslinking involves the formation of a covalent bond between two bases on DNA. (NCI)
National Institutes of Health

Related topics

Related topics

15 relations
Bi-functional Alkylating Agent VAL-083Chromosome StructuresDNA Crosslinking AgentDNA Minor Groove Binding Agent SG2000

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Lanthanoplatins: emissive Eu(iii) and Tb(iii) complexes staining nucleoli targeted through Pt-DNA crosslinking.
Two highly luminescent water-soluble heterometallic LnPt2 complexes, [{cis-PtCl(NH3)2}2Ln(L)(H2O)](NO3)2 (Ln = Eu (1), Tb (2… 
2004
2004
Structure-activity study with bioreductive benzoquinone alkylating agents: effects on DT-diaphorase-mediated DNA crosslink and strand break formation in relation to mechanisms of cytotoxicity
PurposeStructure-activity studies were carried out with the model bioreductive alkylating agent benzoquinone mustard (BM) and its… 
2001
2001
Gamma and Ultraviolet Radiation Cause DNA Crosslinking in the Presence of Metal Ions at High pH ¶
M‐DNA is a novel duplex conformation in which metal ions such as Co2+, Ni2+ or Zn2+ replace the imino protons of every base pair… 
1995
1995
Molecular dynamics simulations of chlorambucil/DNA adducts. A structural basis for the 5'-GNC interstrand DNA crosslink formed by nitrogen mustards.
The alkylation of DNA by chlorambucil has been studied using a computational approach. Molecular dynamics simulations were… 
Highly Cited
1994
Highly Cited
1994
Interstrand DNA crosslinking induced by anthracyclines in tumour cells.
Highly Cited
1994
Highly Cited
1994
Relevance of interstrand DNA crosslinking induced by anthracyclines for their biological activity.
Highly Cited
1993
Highly Cited
1993
Cellular and chromosomal hypersensitivity to DNA crosslinking agents and topoisomerase inhibitors in the radiosensitive Chinese hamster irs mutants: phenotypic similarities to ataxia telangiectasia…
The mutants irs1, irs2 and irs3 were previously isolated from the Chinese hamster line V79-4 on the basis of their… 
1982
1982
Thermal enhancement of X-ray-induced DNA crosslinking.
Ionizing radiation appears to crosslink nuclear DNA with chromosomal proteins. Important cellular processes such as transcription… 
1981
1981
DNA crosslinking and cell survival in human lymphoid cells treated with 8-methoxypsoralen and long wavelength ultraviolet radiation.
1975
1975
Lack of increase in DNA crosslinking in Drosophila melanogaster with age.
Adult Drosophila melanogaster fruit flies ranging in age from 2 to 7.5 weeks with a median colony survival time of 6.4 weeks at… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)