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L 783281

Known as: demethylasterriquinone B1, demethyl-asterriquinone B1, demethylasterriquinone B-1 
National Institutes of Health

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Papers overview

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2014
2014
Abstract 20574: Selective Activation of the PI3K/Akt Pathway With the Insulin Mimetic Demethylasterriquinone B1 Reverses Neuroinflammatory-Mediated Blood-Brain Barrier Dysfunction in Mice
Blood-brain barrier (BBB) dysfunction is a hallmark of neuroinflammation brought on by pathologies such as stroke and amyloid… 
2008
2008
Demethylasterriquinone B-1對大白鼠胰臟分泌胰島素之影響
The development of an orally insulin mimetic drug has been the way for the treatment of diabetes mellitus. In order to discover a… 
2007
2007
Effect of demethylasterriquinone b1 in hypertension associated vascular endothelial dysfunction.
Highly Cited
2005
Highly Cited
2005
Methyl scanning: total synthesis of demethylasterriquinone B1 and derivatives for identification of sites of interaction with and isolation of its receptor(s).
The principle of methyl scanning is proposed for determination of the sites of interaction between biologically active small… 
2002
2002
Effect of the insulin mimetic L-783,281 on intracellular Ca2+ and insulin secretion from pancreatic beta-cells.
L-783,281, an antidiabetic fungal metabolite that has previously been shown to activate insulin signaling in CHO cells, was… 
2002
2002
Glucose-dependent promotion of insulin release from mouse pancreatic islets by the insulin-mimetic compound L-783,281.
An insulin-mimetic compound (L-783,281) was used in an attempt to determine the role of the beta-cell insulin receptor (IR) on… 
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