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L 754030
Known as:
L 754,030
, L-754,030
, L-754030
National Institutes of Health
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Related topics
Related topics
1 relation
Broader (1)
aprepitant
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2012
Review
2012
Potential of Substance P Antagonists as Antiemetics
P. Diemunsch
,
L. Grélot
Drugs
2012
Corpus ID: 25136161
The introduction of serotonin 5-HT3 receptor antagonists into clinical practice allowed for a dramatic improvement in the…
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2006
2006
Intussuscepting giant liposarcoma of the oesophagus.
L. Di Mascio
,
L. Gamble
,
S. Wajed
,
M. Winslet
Journal of postgraduate medicine
2006
Corpus ID: 11671037
1. Pandey CK, Priye S, Ambesh SP, Singh S, Singh U, Singh PK. Prophylactic gabapentin for prevention of postoperative nausea and…
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Review
2005
Review
2005
Aprepitant: A Novel Antiemetic for Chemotherapy-Induced Nausea and Vomiting
Alison M Massaro
,
K. L. Lenz
The Annals of pharmacotherapy
2005
Corpus ID: 2666111
OBJECTIVE: To evaluate the safety and efficacy of aprepitant in the prevention of acute and delayed chemotherapy-induced nausea…
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Highly Cited
2001
Highly Cited
2001
Prevention of cisplatin-induced emesis by the oral neurokinin-1 antagonist, MK-869, in combination with granisetron and dexamethasone or with dexamethasone alone.
D. Campos
,
J. R. Pereira
,
+9 authors
B. Gertz
Journal of clinical oncology : official journal…
2001
Corpus ID: 22142002
PURPOSE The NK1-receptor antagonist MK-869 (L-754,030) has demonstrated antiemetic activity in humans receiving chemotherapy…
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Highly Cited
2001
Highly Cited
2001
Comparison of L-758,298, a prodrug for the selective neurokinin-1 antagonist, L-754,030, with ondansetron for the prevention of cisplatin-induced emesis.
V. Cocquyt
,
S. Van Belle
,
+10 authors
B. Gertz
European journal of cancer
2001
Corpus ID: 553122
Highly Cited
2000
Highly Cited
2000
The novel NK1 receptor antagonist MK–0869 (L–754,030) and its water soluble phosphoryl prodrug, L–758,298, inhibit acute and delayed cisplatin-induced emesis in ferrets
F. D. Tattersall
,
W. Rycroft
,
M. Cumberbatch
,
G. Mason
,
R. Hargreaves
Neuropharmacology
2000
Corpus ID: 25883454
2000
2000
Reply: will changing the testing paradigms show that NK1 receptor antagonists are analgesic in humans?
R. Hill
2000
Corpus ID: 72018813
Highly Cited
1999
Highly Cited
1999
Reduction of cisplatin-induced emesis by a selective neurokinin-1-receptor antagonist. L-754,030 Antiemetic Trials Group.
R. Navari
,
R. Reinhardt
,
+9 authors
B. Gertz
The New England journal of medicine
1999
Corpus ID: 7483962
BACKGROUND The localization of substance P in brain-stem regions associated with vomiting, and the results of studies in ferrets…
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1999
1999
Substance P-induced vasodilatation is mediated by the neurokinin type 1 receptor but does not contribute to basal vascular tone in man.
D. Newby
,
D. Sciberras
,
+5 authors
D. Webb
British journal of clinical pharmacology
1999
Corpus ID: 21027385
AIMS Following intravenous administration of its prodrug, L-758,298, we assessed the pharmacodynamics of L-754,030, a novel and…
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Review
1999
Review
1999
Neurokinin Antagonism and Chemotherapy-Induced Emesis
F. Shanahan
,
G. O'sullivan
American Journal of Gastroenterology
1999
Corpus ID: 37674526
Chemotherapy-induced nausea and vomiting are important, distressing, and occasionally disabling problems that confound the…
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