L 754030

Known as: L 754,030, L-754,030, L-754030 
 

Topic mentions per year

Topic mentions per year

1999-2005
02419992005

Papers overview

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Review
2005
Review
2005
OBJECTIVE To evaluate the safety and efficacy of aprepitant in the prevention of acute and delayed chemotherapy-induced nausea… (More)
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Review
2002
Review
2002
  • Drugs in R&D
  • 2002
 
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2001
2001
PURPOSE The NK1-receptor antagonist MK-869 (L-754,030) has demonstrated antiemetic activity in humans receiving chemotherapy… (More)
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2001
2001
Substance P is localised in brainstem regions associated with emesis. Based on studies in the ferret, it was postulated that a… (More)
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2000
2000
The anti-emetic profile of the novel brain penetrant tachykinin NK1 receptor antagonist MK-0869 (L-754,030) 2-(R)-(1-(R)-(3,5-bis… (More)
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Review
2000
Review
2000
The introduction of serotonin 5-HT3 receptor antagonists into clinical practice allowed for a dramatic improvement in the… (More)
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Highly Cited
1999
Highly Cited
1999
BACKGROUND The localization of substance P in brain-stem regions associated with vomiting, and the results of studies in ferrets… (More)
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1999
1999
AIMS Following intravenous administration of its prodrug, L-758,298, we assessed the pharmacodynamics of L-754,030, a novel and… (More)
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Review
1999
Review
1999
Chemotherapy-induced nausea and vomiting are important, distressing, and occasionally disabling problems that confound the… (More)
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1999
1999
  • Drugs in R&D
  • 1999
 
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