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L 644711

Known as: L-644,711, L-644711 
National Institutes of Health

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Fluorenes

Papers overview

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1998
1998
Pharmacological characterization of swelling-induced D-[3H]aspartate release from primary astrocyte cultures.
During stroke or head trauma, extracellular K+ concentration increases, which can cause astrocytes to swell. In vitro, such… 
Highly Cited
1996
Highly Cited
1996
Release of [3H]-d-Aspartate from Primary Astrocyte Cultures in Response to Raised External Potassium
There are significant Ca2+-independent increases in extracellular glutamate and aspartate during various CNS insults such as… 
1995
1995
Hypoosmotic volume regulation and osmolyte transport in astrocytes is blocked by an anion transport inhibitor, L-644,711
1994
1994
Loop diuretic derivative L-644,711 inhibits K(+)-stimulated cellular injury in neonatal guinea pig cortical astrocytes.
An early pathological rise in extracellular K+ following acute hypoxia results in Cl- uptake into astrocytes through the Cl/HCO3… 
1992
1992
In vitro evidence supporting two mechanisms of action for the anion transport inhibitor L-644,711 in cerebral ischaemia.
L-644,711 is a novel anion channel inhibitor which has previously been shown to decrease brain injury in two related rabbit… 
1991
1991
L‐644,711, a Novel Anion Transport Inhibitor, Increases Isoflurane MAC in Rats
The effect of the anion transport inhibitor L-644,711 on isoflurane MAC was determined in rats (n=24). After baseline MAC… 
1989
1989
Astrocytic swelling in traumatic-hypoxic brain injury. Beneficial effects of an inhibitor of anion exchange transport and glutamate uptake in glial cells.
Swelling of brain slices is shown to occur in response to elevated potassium levels or glutamate, which is accompanied by… 
1989
1989
Hyponatremia-induced brain edema in guinea pigs is reduced by treatment with the novel anion transport inhibitor L-644,711.
1988
1988
Ultrastructural features of a brain injury model in cat
SummaryWe present qualitative and quantitative ultrastructural observations on the changes induced in neuroglia and blood vessels… 
1988
1988
Treatment of tyramine-induced brain edema with anion transport inhibitor L-644,711.
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