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Kv1.1 Potassium Channel

Known as: Kv1.1 Potassium Channel [Chemical/Ingredient], Potassium Channel, Kv1.1, KCNA1 Potassium Channel 
A delayed rectifier subtype of shaker potassium channels that is commonly mutated in human episodic ATAXIA and MYOKYMIA.
National Institutes of Health

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In BloodKCNA1 geneProcess of secretionagonists
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Papers overview

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2012
2012
Identification of Selective Inhibitors of the Potassium Channel Kv1.1–1.2(3) by High-Throughput Virtual Screening and Automated Patch Clamp
Abstract Two voltage-dependent potassium channels, Kv1.1 (KCNA1) and Kv1.2 (KCNA2), are found to co-localize at the… Expand
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2007
2007
Structural consequences of Kcna1 gene deletion and transfer in the mouse hippocampus.
PURPOSE Mice lacking the Kv1.1 potassium channel alpha subunit encoded by the Kcna1 gene develop recurrent behavioral seizures… Expand
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Highly Cited
2004
Highly Cited
2004
Tonotopic Gradients of Membrane and Synaptic Properties for Neurons of the Chicken Nucleus Magnocellularis
Nucleus magnocellularis (NM) is a division of the avian cochlear nucleus that extracts the timing of auditory signals. We… Expand
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2003
2003
Hyperexcitability of CA3 pyramidal cells in mice lacking the potassium channel subunit Kv1.1.
PURPOSE To investigate further the membrane properties and postsynaptic potentials of the CA3 pyramidal cells in mice that… Expand
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2002
2002
Episodic Ataxia Type 1 Mutations in the Human Kv1.1 Potassium Channel Alter hKvβ1-Induced N-Type Inactivation
Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder affecting both central and peripheral nerve function… Expand
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Highly Cited
2000
Highly Cited
2000
Clinical, genetic, and expression studies of mutations in the potassium channel gene KCNA1 reveal new phenotypic variability.
Episodic ataxia type 1 (EA1) is an autosomal dominant central nervous system potassium channelopathy characterized by brief… Expand
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Review
1999
Review
1999
Developmental Seizure Susceptibility of Kv1.1 Potassium Channel Knockout Mice
Potassium channels play a critical role in limiting neuronal excitability. Mutations in certain voltage-gated potassium channels… Expand
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1999
1999
Protein kinase C inhibits Kv1.1 potassium channel function.
The regulation by protein kinase C (PKC) of recombinant voltage-gated potassium (K) channels in frog oocytes was studied. Phorbol… Expand
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1999
1999
Protein kinase C inhibits Kv1.1 potassium channel function.
The regulation by protein kinase C (PKC) of recombinant voltage-gated potassium (K) channels in frog oocytes was studied. Phorbol… Expand
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1998
1998
Characterization of three episodic ataxia mutations in the human Kv1.1 potassium channel.
Episodic ataxia (EA) is a rare inherited neurological disorder due to mutation in the voltage-dependent Kv1.1 potassium channel… Expand
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