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Krueppel-Like Factor 1

Known as: EKLF, Erythroid Transcription Factor, Erythroid-Specific Transcription Factor EKLF 
Krueppel-like factor 1 (362, ~38 kDa) is encoded by the human KLF1 gene. This protein is involved in transcriptional regulation during erythroid cell… 
National Institutes of Health

Related topics

Related topics

10 relations
CYS2-HIS2 Zinc FingersCell Differentiation processDNA-Binding ProteinsGATA1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2013
2013
Molecular Analysis of the Rare In(Lu) Blood Type: Toward Decoding the Phenotypic Outcome of Haploinsufficiency for the Transcription Factor KLF1
KLF1 encodes an erythroid transcription factor, whose essential function in erythropoiesis has been demonstrated by extensive… 
2010
2010
EKLF Directly Activates the p21WAF1/CIP1 Gene by Proximal Promoter and Novel Intronic Regulatory Regions during Erythroid Differentiation
ABSTRACT The switch from proliferation to differentiation during the terminal stages of erythropoiesis is a tightly controlled… 
Highly Cited
2008
Highly Cited
2008
Tumor necrosis factor alpha inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation.
2007
2007
EKLF and KLF2 have compensatory roles in embryonic beta-globin gene expression and primitive erythropoiesis.
Review
2002
Review
2002
ChIPs of the beta-globin locus: unraveling gene regulation within an active domain.
Recent studies of beta-globin gene expression have concentrated on the analysis of factor binding and chromatin structure within… 
Highly Cited
1998
Highly Cited
1998
Key Residues Characteristic of GATA N-fingers Are Recognized By FOG*
Protein-protein interactions play significant roles in the control of gene expression. These interactions often occur between… 
1997
1997
NF-E2p18/mafK is required in DMSO-induced differentiation of Friend erythroleukemia cells by enhancing NF-E2 activity
When Friend murine erythroleukemia (F-MEL) cells are induced to differentiate by dimethylsulfoxide (DMSO), erythroid-specific… 
1997
1997
LIM-only protein Lmo2 forms a protein complex with erythroid transcription factor GATA-1.
The LIM-only protein Lmo2, originally identified as an oncogenic protein in human T cell leukemia, is essential for… 
Highly Cited
1991
Highly Cited
1991
Structure and promoter activity of the gene for the erythroid transcription factor GATA-1.
We have cloned the gene for the chicken erythroid transcription factor GATA-1 (formerly Eryf1, NF-E1, or GF-1). The gene is… 
Highly Cited
1990
Highly Cited
1990
Regulated expression of globin chains and the erythroid transcription factor GATA-1 during erythropoiesis in the developing mouse
Erythropoiesis in vertebrates is characterized by sequential changes in erythropoietic site, erythroblast morphology, and… 
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