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Krueppel-Like Factor 1

Known as: EKLF, Erythroid Transcription Factor, Erythroid-Specific Transcription Factor EKLF 
Krueppel-like factor 1 (362, ~38 kDa) is encoded by the human KLF1 gene. This protein is involved in transcriptional regulation during erythroid cell… 
National Institutes of Health

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CYS2-HIS2 Zinc FingersCell Differentiation processDNA-Binding ProteinsGATA1 protein, human

Papers overview

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2019
2019
Congenital Nonspherocytic Hemolytic Anemia Caused by Krüppel-Like Factor 1 Gene Variants: Another Case Report
Abstract In this study, we report on a compound heterozygote for variants in the key erythroid transcription factor Krüppel-like… 
2018
2018
KFL1 Gene Variants in α-Thalassemia Individuals with Increased Fetal Hemoglobin in a Chinese Population
Abstract Krüppel-like factor 1 (KLF1) is a pleiotropic erythroid transcription factor that is a regulator of definitive… 
2009
2009
The inhibitory effect of the proinflammatory cytokine TNFalpha on erythroid differentiation involves erythroid transcription factor modulation.
The hematopoietic transcription factor GATA-1 regulates the expression of several genes associated with differentiation of… 
2009
2009
EKLF / KLF 1 Controls Cell Cycle Entry via Direct Regulation of E 2 f 2 *
Differentiation of erythroid cells requires precise control over the cell cycle to regulate the balance between cell… 
2008
2008
Involvement of Sp1/Sp3 in the activation of the GATA-1 erythroid promoter in K562 cells
GATA-1 is a hematopoietic transcription factor that is essential for the terminal maturation of proerythroblasts, megakaryocytic… 
2007
2007
Identification of Target Genes of an Erythroid Transcription Factor Complex Containing SCL (TAL1).
Haematopoiesis is the process whereby haematopoietic stem cells give rise to mature blood cell lineages. The SCL (TAL1) gene… 
2004
2004
Chromatin Remodeling of the Mouse AHSP Gene Requires EKLF.
Alpha-Hemoglobin Stabilizing Protein (AHSP) is an erythroid-specific protein that binds to α-globin, preventing precipitation of… 
2000
2000
EKLF : un facteur clé pour l’expression du gène ß de globine et la commutationd’expression des gènes de globine au cours du développement
Le locus b-globine est depuis longtemps un modele d’etude des mecanismes de la specificite tissulaire d’expression des genes et… 
1997
1997
The human erythroid-specific transcription factor EKLF localizes to chromosome 19p13.12-p13.13.
Erythroid Krüppel-like factor (EKLF) is a trans-acting factor that binds specifically to the beta-globin promoter CACCC box. EKLF… 
1994
1994
Direct analysis of native and chimeric GATA specific DNA binding proteins from Aspergillus nidulans.
In Aspergillus nidulans the regulatory gene areA is responsible for mediating nitrogen metabolite repression. The areA product… 
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