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Kremezin

 
National Institutes of Health

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AST 120

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Mechanistic insight of diabetic nephropathy and its pharmacotherapeutic targets: An update.
Diabetic nephropathy (DN), a chronic complication of diabetes, is charecterized by glomerular hypertrophy, proteinuria, decreased… Expand
2011
2011
Intestinal-Renal Syndrome: Mirage or Reality?
  • E. Ritz
  • Blood Purification
  • 2011
    • Corpus ID: 19782395
The recent interest in the role of the intestine in the cardiovascular stability of uremic patients, specifically on dialysis… Expand
Review
2010
Review
2010
The Gut: The Forgotten Organ in Uremia?
Part of the uremic retention solutes are generated in the intestine, but this option is rarely discussed in the literature. In… Expand
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2010
2010
Cardiorenal protective effect of the oral uremic toxin absorbent AST-120 in chronic heart disease patients with moderate CKD.
BACKGROUND The detailed mechanisms and treatment methods of chronic kidney disease (CKD) in patients with chronic heart failure… Expand
Highly Cited
2008
Highly Cited
2008
AST-120 (Kremezin) initiated in early stage chronic kidney disease stunts the progression of renal dysfunction in type 2 diabetic subjects.
There is little clinical evidence when AST-120 should be prescribed for subjects with early stage overt diabetic nephropathy. We… Expand
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2007
2007
Oral administration of AST-120 (Kremezin) is a promising therapeutic strategy for advanced glycation end product (AGE)-related disorders.
The pathological role of the non-enzymatic modification of proteins by reducing sugars has become increasingly evident in various… Expand
2007
2007
Indoxyl sulfate-lowering capacity of oral sorbents affects the prognosis of kidney function and oxidative stress in chronic kidney disease.
  • K. Taki, T. Niwa
  • Journal of renal nutrition : the official journal…
  • 2007
    • Corpus ID: 2265167
OBJECTIVES Indoxyl sulfate shows nephrotoxicity and is a stimulating factor for progression of chronic kidney disease (CKD). This… Expand
Highly Cited
2006
Highly Cited
2006
A multicenter, randomized, double-blind, placebo-controlled, dose-ranging study of AST-120 (Kremezin) in patients with moderate to severe CKD.
BACKGROUND AST-120 (Kremezin; Kureha Chemical Industry Co Ltd, Tokyo, Japan) is an orally administered adsorbent showing… Expand
Highly Cited
2004
Highly Cited
2004
Oral Adsorbent AST-120 Decreases Carotid Intima-Media Thickness and Arterial Stiffness in Patients with Chronic Renal Failure
Background/Aim: Intima media thickness (IMT) and stiffness of the carotid arteries is related to coronary artery disease, and… Expand
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2002
2002
Effects of Oral Adsorbent AST-120 (Kremezin®) on Renal Function and Glomerular Injury in Early-Stage Renal Failure of Subtotal Nephrectomized Rats
The aim of the present study was to determine if treatment with an oral adsorbent (AST-120, Kremezin®) might decrease the urinary… Expand
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