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Kras gene mutation

Known as: v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog Gene Mutation, KRAS2 Gene Mutation, KRAS-2 Gene Mutation 
A change in the nucleotide sequence of the KRAS gene.
National Institutes of Health

Related topics

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Ampulla of Vater Villous AdenomaAppendix Mucinous CystadenomaAtypical Adenomatous Lung HyperplasiaBranch Duct Pancreatic Intraductal Papillary-Mucinous Neoplasm

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
A novel KRAS gene mutation report in sporadic colorectal cancer, from Northwest of Iran
While the role of KRAS gene mutations has been widely accepted for predicting responses to anti‐EGFR therapy in patients with… 
2014
2014
Prevalence of KRAS gene mutation in ampullary cancer in Thai patients.
e15175 Background: Ampullary cancer has been regards to have a better prognosis than the other periampullary tumors. Certain data… 
2013
2013
[KRAS gene mutation in colorectal cancer].
BACKGROUND KRAS oncogene is involved in colorectal carcinogenesis in 22 to 45% of cases. AIM To determine the frequency, types… 
2013
2013
KRAS gene mutations are more common in colorectal villous adenomas and in situ carcinomas than in carcinomas.
We have evaluated the frequency of KRAS gene mutations during the critical transition from villous adenoma to colorectal… 
Review
2013
Review
2013
Clinical significance of KRAS gene mutation and epidermal growth factor receptor expression in Japanese patients with squamous cell carcinoma of the larynx, oropharynx and hypopharynx
PurposeThe significance of epidermal growth factor receptor (EGFR) signaling has been recognized in various cancers and anti-EGFR… 
Review
2013
Review
2013
KRAS gene mutation status and sensitivity to pemetrexed: A retrospective analysis.
e19154 Background: KRAS is the most frequently mutated oncogene (25%) in lung adenocarcinoma. KRAS mutations are a negative… 
2012
2012
[Detection of KRAS gene mutation and its clinical significance in colorectal adenocarcinoma].
OBJECTIVE To explore the clinical significance of KRAS mutation detection in colorectal adenocarcinoma. METHODS Paraffin… 
Review
2011
Review
2011
Molecular differences in the KRAS gene mutation between a primary tumor and related metastatic sites - case report and a literature review.
In recent years the the set of diagnostic tools in colorectal cancers has been extended by the assessment of the KRAS gene status… 
2011
2011
[The role of KRAS gene mutation testing in colorectal cancer--a predictive biomarker of response to EGFR inhibitors therapy].
Activation of KRAS oncogene has been implicated in colorectal carcinogenesis. KRAS mutations can be detected in more than 30% of… 
2011
2011
[Analysis of the correlation with KRAS gene mutation status and the benefit of cetuximab plus irinotecan as third- line chemotherapy for the Treatment of unresectable metastatic colorectal cancer].
Mutation of the KRAS gene in patients with metastatic colorectal cancer(mCRC)has been established as a predictive marker of poor… 
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