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Kit Ligand, human

Known as: C-Kit Ligand, Steel Factor, MGF Stem Cell Factor 
A substance that causes blood stem cells (cells from which other types of cells develop) to change into different types of blood cells and increases… 
National Institutes of Health

Related topics

Related topics

20 relations
Bone MarrowCytokine GeneCytokine Receptor BindingCytokine Signaling

Broader (1)

Stem Cell Factor

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Growth, phenotype, and function of human intestinal mast cells are tightly regulated by transforming growth factor β1
Background and aims: Transforming growth factor β1 (TGF-β1) is expressed in the healthy human intestine and controls mucosal… 
Highly Cited
2004
Highly Cited
2004
Induction of Stem Cell Factor/c-Kit/Slug Signal Transduction in Multidrug-resistant Malignant Mesothelioma Cells*
Malignant mesothelioma (MM) is strongly resistant to conventional chemotherapy by unclear mechanisms. We and others have… 
Highly Cited
2001
Highly Cited
2001
Avoidance of stimulation improves engraftment of cultured and retrovirally transduced hematopoietic cells in primates.
Recent reports suggest that cells in active cell cycle have an engraftment defect compared with quiescent cells. We used nonhuman… 
Highly Cited
1999
Highly Cited
1999
Recombinant human (rh)IL-4-mediated apoptosis and recombinant human IL-6-mediated protection of recombinant human stem cell factor-dependent human mast cells derived from cord blood mononuclear cell…
Although stem cell factor (SCF) appears to be the major growth factor for human mast cells, other factors undoubtedly play… 
Highly Cited
1998
Highly Cited
1998
Inverse targeting of retroviral vectors: selective gene transfer in a mixed population of hematopoietic and nonhematopoietic cells.
We previously reported that retroviral vectors displaying epidermal growth factor (EGF) as part of a chimeric envelope… 
Highly Cited
1997
Highly Cited
1997
Age-dependent intestinal lymphoproliferative disorder due to stem cell factor receptor deficiency: parameters in small and large intestine.
Signaling through c-Kit/stem cell factor (SCF) is crucial for normal development of erythroid and myeloid hematopoietic… 
Highly Cited
1997
Highly Cited
1997
Thrombopoietin augments ex vivo expansion of human cord blood-derived hematopoietic progenitors in combination with stem cell factor and flt3 ligand
We studied the effects of stem cell factor (SCF) and flt3 ligand (FL) on the ex vivo expansion of human umbilical cord blood (CB… 
Highly Cited
1992
Highly Cited
1992
Expression of cytokines and their receptors by human thymocytes and thymic stromal cells.
The repertoire of cytokine and cytokine receptor mRNA expressed by unstimulated human thymocytes and thymic stromal cells was… 
Highly Cited
1992
Highly Cited
1992
Interaction of human bone marrow fibroblasts with megakaryocytes: role of the c-kit ligand.
Human kit ligand (KL), also known as stem cell factor (SCF), steel factor, or mast cell growth factor, is a recently identified… 
Highly Cited
1991
Highly Cited
1991
IL-4 regulates c-kit proto-oncogene product expression in human mast and myeloid progenitor cells.
The c-kit proto-oncogene encodes the receptor for a novel hemopoietic cytokine, termed stem cell factor (SCF) or mast cell growth… 
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