Kearns-Sayre syndrome

Known as: CPEO with Myopathies, Ophthalmoplegia, Progressive External, With Ragged-Red Fibers, Kearns Syndrome 
A mitochondrial disorder featuring the triad of chronic progressive EXTERNAL OPHTHALMOPLEGIA, cardiomyopathy (CARDIOMYOPATHIES) with conduction block… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1935-2018
05010019352017

Papers overview

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2005
2005
Kearns–Sayre syndrome (KSS) is a mitochondrial disease caused by large deletions in mitochondrial DNA (mtDNA). In most patients… (More)
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1990
1990
The neuropathological changes found at autopsy in a case of Kearns-Sayre syndrome are described. We have previously analyzed the… (More)
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Highly Cited
1990
Highly Cited
1990
ABSTRACT: We have performed morphologic and biochemical studies in three pediatric cases of Kearns-Sayre syndrome. All cases had… (More)
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Highly Cited
1989
Highly Cited
1989
We investigated the correlations of deletions of mitochondrial DNA in skeletal muscle with clinical manifestations of… (More)
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1989
1989
A 25-year-old woman with Kearns-Sayre syndrome (KSS) had complete external ophthalmoplegia, short stature, ataxia, cardiac… (More)
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Highly Cited
1989
Highly Cited
1989
The muscle mitochondria of a patient with Kearns-Sayre/chronic external ophthalmoplegia plus syndrome were found to be completely… (More)
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Highly Cited
1988
Highly Cited
1988
We have identified large-scale deletions in muscle mitochondrial DNA (mtDNA) in seven of seven patients with Kearns-Sayre… (More)
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1985
1985
Examination of the retinal tissues obtained at necropsy from a 14-year-old boy with Kearns-Sayre syndrome showed marked… (More)
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1980
1980
External ophthalmoplegia, retinal pigmentary degeneration, and heart block constitute the Kearns-Sayre syndrome. Skeletal muscle… (More)
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1978
1978
The history, clinical findings, and postmortem examination of a patient with Kearns-Sayre syndrome are presented. In addition to… (More)
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