Acidosis, Lactic

Known as: ACIDOSIS LACTIC, lactacidosis, Lactic acidosis 
Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases… (More)

Topic mentions per year

Topic mentions per year

1943-2018
010020019432017

Papers overview

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Highly Cited
2008
Highly Cited
2008
The tumor microenvironment has a significant impact on tumor development. Two important determinants in this environment are… (More)
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Highly Cited
2006
Highly Cited
2006
OBJECTIVE Open-label studies indicate that oral dichloroacetate (DCA) may be effective in treating patients with congenital… (More)
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2003
2003
Lactate is a byproduct of glycolysis. In the energyproducing metabolism of glucose two distinct processes occur. The first series… (More)
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Highly Cited
2000
Highly Cited
2000
Although metformin is widely used for the treatment of non-insulin-dependent diabetes, its mode of action remains unclear. Here… (More)
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Highly Cited
1996
Highly Cited
1996
Early lactic acidosis during exercise and abnormal skeletal muscle function have been reported in chronic obstructive pulmonary… (More)
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Highly Cited
1995
Highly Cited
1995
BACKGROUND We describe severe and unexpected multisystem toxicity that occurred during a study of the antiviral nucleoside… (More)
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Highly Cited
1992
Highly Cited
1992
BACKGROUND Mortality is very high in lactic acidosis, and there is no satisfactory treatment other than treatment of the… (More)
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Highly Cited
1990
Highly Cited
1990
STUDY OBJECTIVE To determine whether correction of acidemia using bicarbonate improves hemodynamics in patients who have lactic… (More)
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Highly Cited
1984
Highly Cited
1984
We report on two patients who have a mitochondrial myopathy, encephalopathy, lactic acidosis, and recurrent cerebral insults that… (More)
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Highly Cited
1981
Highly Cited
1981
The influence of severe tissue lactic acidosis during incomplete brain ischemia (30 min) on cortex morphology was studied in… (More)
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