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Acidosis, Lactic

Known as: ACIDOSIS LACTIC, LACTIC ACIDOSIS, lactacidosis 
Acidosis caused by accumulation of lactic acid more rapidly than it can be metabolized. It may occur spontaneously or in association with diseases… Expand
National Institutes of Health

Related topics

Related topics

45 relations
3-METHYLGLUTACONIC ACIDURIA WITH DEAFNESS, ENCEPHALOPATHY, AND LEIGH-LIKE SYNDROMEAcid-Base EquilibriumCOMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 11COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 19
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Broader (2)

AcidemiaAcidosis

Narrower (9)

Combined Oxidative Phosphorylation Deficiency 4GRACILE SYNDROME (disorder)Lactic Acidosis, Congenital Infantile, Due To Lad DeficiencyMitochondrial myopathy with lactic acidosis
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Papers overview

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Review
2010
Review
2010
Risk of fatal and nonfatal lactic acidosis with metformin use in type 2 diabetes mellitus.
BACKGROUND Metformin is an oral anti-hyperglycemic agent that has been shown to reduce total mortality compared to other anti… Expand
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Highly Cited
2008
Highly Cited
2008
Metformin, Sulfonylureas, or Other Antidiabetes Drugs and the Risk of Lactic Acidosis or Hypoglycemia
OBJECTIVE Lactic acidosis has been associated with use of metformin. Hypoglycemia is a major concern using sulfonylureas. The aim… Expand
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Highly Cited
2000
Highly Cited
2000
Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain.
Although metformin is widely used for the treatment of non-insulin-dependent diabetes, its mode of action remains unclear. Here… Expand
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Highly Cited
1998
Highly Cited
1998
Lactic acidosis in patients with diabetes treated with metformin.
To the Editor: From May 1995, when metformin was introduced in the United States, through June 30, 1996, the Food and Drug… Expand
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Review
1997
Review
1997
Bovine acidosis: implications on laminitis.
Bovine lactic acidosis syndrome is associated with large increases of lactic acid in the rumen, which result from diets that are… Expand
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Highly Cited
1995
Highly Cited
1995
Hepatic failure and lactic acidosis due to fialuridine (FIAU), an investigational nucleoside analogue for chronic hepatitis B.
BACKGROUND We describe severe and unexpected multisystem toxicity that occurred during a study of the antiviral nucleoside… Expand
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Review
1990
Review
1990
Gas exchange theory and the lactic acidosis (anaerobic) threshold.
The physiological requirements of performing exercise above the anaerobic threshold are considerably more demanding than for… Expand
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Highly Cited
1990
Highly Cited
1990
A mutation in the tRNALeu(UUR) gene associated with the MELAS subgroup of mitochondrial encephalomyopathies
MITOCHONDRIAL encephalomyopathies are usually divided into three distinct clinical subgroups: (1) mitochondrial myopathy… Expand
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Highly Cited
1984
Highly Cited
1984
Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: a distinctive clinical syndrome.
We report on two patients who have a mitochondrial myopathy, encephalopathy, lactic acidosis, and recurrent cerebral insults that… Expand
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Review
1971
Review
1971
Lactic acidosis.
  • Arnold S. Relman
  • Transactions of the American Clinical and…
  • 1971
    • Corpus ID: 849304
 
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