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Kanamycin

Known as: Kanamycin [Chemical/Ingredient], D-Streptamine, O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1-6)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1-4))-2-deoxy-, Kanamycin Complex 
An aminoglycoside antibiotic with antimicrobial property. Amikacin irreversibly binds to the bacterial 30S ribosomal subunit, specifically in contact… 
National Institutes of Health

Related topics

Related topics

34 relations

Narrower (10)

1-N-(2-aminoethoxycarbonyl)kanamycin A3'-chloro-3'-deoxykanamycin A3'-deoxy-3'-fluorokanamycin A3'-deoxy-3'-fluorokanamycin B
AminoglycosidesAntimycobacterial drug poisoningBacterial InfectionsDecreased Protein Synthesis [PE]

Broader (4)

Anti-Bacterial AgentsAntibiotics, AminoglycosideAntitubercular AgentsProtein Synthesis Inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1981
1981
Resistance mechanisms of kanamycin-, neomycin-, and streptomycin-producing streptomycetes to aminoglycoside antibiotics.
Streptomyces kanamyceticus ISP5500, S. fradiae ISP5063 and S. griseus ISP5236, which produce kanamycin, neomycin or streptomycin… 
Review
1973
Review
1973
Letter: Kanamycin phosphotransferase. I. Mechanism of cross resistance between kanamycin and lividomycin.
As reported in a previous paper1}, kanamycin phosphotransferase which is produced by Escherichia coli K12 ML1629 and ML1410 R81… 
1973
1973
Comparative In Vitro Activity of Three Aminoglycosidic Antibiotics: BB-K8, Kanamycin, and Gentamicin
Kanamycin, BB-K8, and gentamicin were tested in parallel against 1,037 bacterial strains isolated from clinical material. The… 
1971
1971
Synthesis of 3'.4'-dideoxyneamine active aginst kanamycin-resistant E. coli and P. aeruginosa.
protected by carbomethoxy chloride in aqueous acetone (1: 1) to give tetra-N-carbomethoxyneamine (I) in a yield of 87%, which was… 
Highly Cited
1968
Highly Cited
1968
Inactivation of kanamycin, neomycin, and streptomycin by enzymes obtained in cells of Pseudomonas aeruginoa.
Ten strains of Pseudomonas aeruginosa were disrupted and centrifuged. The supernatant fluids from centrifugation at 105,000 x g… 
Highly Cited
1968
Highly Cited
1968
Isolation of kanamycin and paromamine inactivated by E. coli carrying R factor.
Kanamycin and paromamine were inactivated in the presence of ATP and Mg++ by an enzyme solution obtained from E. coli carrying R… 
Highly Cited
1967
Highly Cited
1967
Kanamycin dosage and levels in ear and other organs.
THE BASIC STREPTOMYCES antibiotics, streptomycin and kanamycin, are valuable and effective means in the hands of a physician. In… 
Highly Cited
1967
Highly Cited
1967
Removal and absorption of antibiotics in patients with renal failure undergoing peritoneal dialysis. Tetracycline, chloramphenicol, kanamycin, and colistimethate.
Excerpt Gram-negative bacterial infections frequently complicate the management of patients undergoing peritoneal dialysis for… 
1963
1963
RESPIRATORY AND CARDIAC ARREST AFTER INTRAVENOUS ADMINISTRATION OF KANAMYCIN WITH REVERSAL OF TOXIC EFFECTS BY NEOSTIGMINE.
Excerpt The purpose of this report is threefold: [1] to alert physicians to the curare-like effects that kanamycin may have on… 
1960
1960
Enterocolitis due to phage type 54 staphylococci resistant to kanamycin, neomycin, paromomycin and chloramphenicol.
NEOMYCIN has been used for many years. Parenteral administration has been limited because of marked toxicity. The drug has been…