KRN 951

Known as: KRN-951, KRN951 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2013
012320042013

Papers overview

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2014
2014
AIM This study aimed to investigate the mechanism of reversal of multidrug resistance mediated by ABC transporters with tivozanib… (More)
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2013
2013
Proliferation and migration of retinal endothelial cells (REC) are associated with the development of proliferative diabetic… (More)
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Review
2013
Review
2013
Tivozanib hydrochloride monohydrate (tivozanib; formerly KRN-951, AV-951) is a potent pan-VEGF receptor tyrosine kinase inhibitor… (More)
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2011
2011
PURPOSE To assess the maximum tolerated dose (MTD)/dose-limiting toxicities (DLT), safety, pharmacokinetics, and pharmacodynamics… (More)
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2011
2011
BACKGROUND Deregulated expression of vascular endothelial growth factor (VEGF), basic fibroblast growth factor (bFGF) or insulin… (More)
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2008
2008
We assessed the antitumor efficacy of KRN951, a novel tyrosine kinase inhibitor of vascular endothelial growth factor receptors… (More)
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Review
2008
Review
2008
The oral multitargeted kinase inhibitors (MTKI) sunitinib (SU11248, Sutent; Pfi zer, New York) and sorafenib (BAY 43-9006… (More)
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Highly Cited
2006
Highly Cited
2006
Vascular endothelial growth factor (VEGF) and VEGF receptor-1 (VEGFR-1/Flt-1) were shown to be involved in pathological… (More)
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2006
2006
Vascular endothelial growth factor (VEGF) plays a key role in tumor angiogenesis by stimulating the proangiogenic signaling of… (More)
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2006
2006
2034 Background: KRN951 inhibits VEGF induced phosphorylation of VEGF receptors (VEGFR)2 and 1 (IC50 of 0.16 and 0.21 nM) and… (More)
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