Skip to search formSkip to main contentSkip to account menu

KNSTRN protein, human

Known as: Small Kinetochore-Associated Protein, Kinastrin, SKAP 
Small kinetochore-associated protein (316 aa, ~35 kDa) is encoded by the human KNSTRN gene. This protein plays a role in the progression of mitosis.
National Institutes of Health

Related topics

Related topics

11 relations
Cell Cycle ControlCell Cycle ProgressionCentromereChromosome Segregation

Broader (2)

Cell Cycle ProteinsMicrotubule-Associated Proteins

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2017
Highly Cited
2017
Aurora-B kinase pathway controls the lateral to end-on conversion of kinetochore-microtubule attachments in human cells
Human chromosomes are captured along microtubule walls (lateral attachment) and then tethered to microtubule-ends (end-on… 
2012
2012
Mitotic Regulator SKAP Forms a Link between Kinetochore Core Complex KMN and Dynamic Spindle Microtubules*
Background: KMN (KNL/MIS12/NDC80) is a kinetochore constituent essential for chromosome movements in mitosis. Results: KMN… 
Highly Cited
2011
Highly Cited
2011
The astrin–kinastrin/SKAP complex localizes to microtubule plus ends and facilitates chromosome alignment
Kinastrin is identified as a major interacting partner for astrin in mitotic cells, and is required for astrin targeting to… 
2011
2011
CENP-E Kinesin Interacts with SKAP Protein to Orchestrate Accurate Chromosome Segregation in Mitosis*
Background: CENP-E is a kinetochore-associated kinesin responsible for chromosome congression in mitosis. Results: CENP-E… 
2010
2010
Role for ADAP in shear flow-induced platelet mechanotransduction.
Binding of platelets to fibrinogen via integrin alphaIIbbeta3 stimulates cytoskeletal reorganization and spreading. These… 
Highly Cited
2009
Highly Cited
2009
SKAP associates with kinetochores and promotes the metaphase-to-anaphase transition
The spindle assembly checkpoint (SAC) controls the anaphase onset by preventing premature chromosome segregation until bipolar… 
Highly Cited
2005
Highly Cited
2005
Regulation of In Vitro and In Vivo Immune Functions by the Cytosolic Adaptor Protein SKAP-HOM
ABSTRACT SKAP-HOM is a cytosolic adaptor protein representing a specific substrate for the Src family protein tyrosine kinase Fyn… 
Highly Cited
2000
Highly Cited
2000
The Yersinia tyrosine phosphatase YopH targets a novel adhesion‐regulated signalling complex in macrophages
The Yersinia protein tyrosine phosphatase (PTP) YopH is translocated into eukaryotic cells by a type III secretion system that… 
Highly Cited
2000
Highly Cited
2000
Interaction of Linker for Activation of T Cells with Multiple Adapter Proteins in Platelets Activated by the Glycoprotein VI-selective Ligand, Convulxin*
The snake venom toxin convulxin activates platelets through the collagen receptor glycoprotein VI (GPVI)/Fc receptor γ-chain (FcR… 
Highly Cited
1998
Highly Cited
1998
SKAP‐HOM, a novel adaptor protein homologous to the FYN‐associated protein SKAP55 1
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)