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KLLN gene

Known as: KLLN, KILLIN, killin, p53-regulated DNA replication inhibitor 
This gene is involved in both DNA binding and apoptosis regulation.
National Institutes of Health

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Related topics

4 relations
ApoptosisCell Cycle Controldna binding

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KLLN wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Significant role and mechanism of microRNA-143-3p/KLLN axis in the development of coronary heart disease.
Cardiovascular disease predominantly includes coronary heart disease (CHD) and stroke, results in high morbidity and mortality… 
2018
2018
Genomic and epigenetic signatures associated with survival rate in oral squamous cell carcinoma patients
Purpose: Although oral squamous cell carcinoma (OSCC) presents great mortality and morbidity worldwide, the mechanisms behind its… 
2016
2016
Upregulated microRNA-224 promotes ovarian cancer cell proliferation by targeting KLLN
  • Ke HuM. Liang
  • In Vitro Cellular & Developmental Biology…
  • 2016
  • Corpus ID: 29545600
Human epithelial ovarian cancer is a complex disease, with low 5-yr survival rate largely due to the terminal stage at diagnosis… 
2015
2015
Cell cycle specific distribution of killin: evidence for negative regulation of both DNA and RNA synthesis
p53 tumor-suppressor gene is a master transcription factor which controls cell cycle progression and apoptosis. killin was… 
2015
2015
Cell cycle specific distribution of killin: evidencefor negative regulation of both DNA and RNAsynthesis
2014
2014
pKILLIN: a versatile positive-selection cloning vector based on the toxicity of Killin in Escherichia coli.
2014
2014
Germline SDHB/C/D variation and KLLN promoter methylation in endometrial cancer patients with Cowden and Cowden-like syndrome
2014
2014
KLLN as Tumor Suppressor in Cowden Syndrome and Sporadic Breast Cancers
................................................................................................................... 13 CHAPTER 1… 
2013
2013
Germline and somatic KLLN alterations in breast cancer dysregulate G2 arrest.
PTEN is a well-described predisposition gene for Cowden syndrome (CS), a familial cancer syndrome characterized by a high risk of… 
2010
2010
PTEN promoter silencing and Cowden syndrome: the role of epigenetic regulation of KILLIN.
  • D. JelovacB. Park
  • Journal of the American Medical Association (JAMA…
  • 2010
  • Corpus ID: 30575490
THE PHOSPHATASE AND TENSIN HOMOLOG GENE (PTEN) (RefSeq NM_000314) is a tumor suppressor located on the human chromosome 10q arm… 
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