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KL gene

Known as: KLOTHO, Klotho Gene, ALPHA-KLOTHO 
This gene is involved in signaling.
National Institutes of Health

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Related topics

8 relations
AgingCarbohydrate MetabolismHydrolysisKL protein, human

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KL wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2016
Review
2016
Klotho and the Growth Hormone/Insulin-Like Growth Factor 1 Axis: Novel Insights into Complex Interactions.
2016
2016
Decreased Level of Klotho Contributes to Drug Resistance in Lung Cancer Cells: Involving in Klotho-Mediated Cell Autophagy.
Klotho is originally discovered as an anti-aging gene and recently identified as a tumor suppressor in various human cancers… 
2016
2016
Soluble Klotho levels in diabetic nephropathy: relationship with arterial stiffness.
OBJECTIVE In this cross-sectional study, we investigate the relationship between soluble Klotho (s-Klotho) levels, markers of… 
2015
2015
Epigenetic reactivation of p21CIP1/WAF1 and KLOTHO by a combination of bioactive dietary supplements is partially ERα-dependent in ERα-negative human breast cancer cells
Review
2015
Review
2015
α-Klotho's effects on mineral homeostasis are fibroblast growth factor-23 dependent
Purpose of review &agr;-Klotho (Klotho) occurs in three isoforms, a membrane-bound form acting as a coreceptor for fibroblast… 
2014
2014
Klotho attenuates high glucose-induced fibronectin and cell hypertrophy via the ERK1/2-p38 kinase signaling pathway in renal interstitial fibroblasts
Review
2012
Review
2012
Regulation of ion channels by secreted Klotho.
Klotho is an anti-aging protein predominantly expressed in the kidney, parathyroid glands and choroid plexus of the brain. Klotho… 
Review
2009
Review
2009
Klotho gene, phosphocalcic metabolism, and survival in dialysis.
The discovery that two recently identified molecules, klotho and fibroblast growth factor 23 (FGF23), played an important role in… 
2004
2004
Klotho gene variation and expression in 20 inbred mouse strains
A defect in klotho gene expression in the mouse results in a syndrome that resembles human aging, with greatly shortened lifespan… 
Highly Cited
1990
Highly Cited
1990
Demonstration of the heterogeneity of epitopes of the platelet‐specific alloantigen, Baka
It is well known that the platelet‐specific alloantigen, Baka is carried on glycoprotein (GP) IIb, but little is known about the… 
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