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KIR2DL2 wt Allele

Known as: CD158B1, cl-43, NKAT6 
Human KIR2DL2 wild-type allele is located in the vicinity of 19q13.4 and is approximately 15 kb in length. This allele, which encodes killer cell… 
National Institutes of Health

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7 relations
19q13.4Immune responseKIR2DL2 geneKIR2DL2 protein, human
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Papers overview

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Highly Cited
2014
Highly Cited
2014
Acute exercise preferentially redeploys NK-cells with a highly-differentiated phenotype and augments cytotoxicity against lymphoma and multiple myeloma target cells
NK-cells undergo a "licensing" process as they develop into fully-functional cells capable of efficiently killing targets. NK… 
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Highly Cited
2009
Highly Cited
2009
Biomarkers of suppressed natural killer (NK) cell function in metastatic melanoma: Decreased NKG2D and increased CD158a receptors on CD3–CD16+ NK cells
In metastatic melanoma (MM) patients we evaluated natural killer (NK)-cell activity, distribution of several NK receptors and… 
Highly Cited
2006
Highly Cited
2006
The inhibitory receptor IRp60 (CD300a) suppresses the effects of IL-5, GM-CSF, and eotaxin on human peripheral blood eosinophils.
Allergic, inflammatory, and immune responses carried out by eosinophils are regulated by the cross talk between activatory and… 
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Highly Cited
2004
Highly Cited
2004
Expression of chemokine and inhibitory receptors on natural killer cells: effect of immune activation and HIV viremia.
We examined the cell-surface expression of chemokine and natural killer (NK) cell inhibitory receptors (iNKRs) on NK cells from… 
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2001
2001
CD85/LIR-1/ILT2 and CD152 (Cytotoxic T Lymphocyte Antigen 4) Inhibitory Molecules Down-Regulate the Cytolytic Activity of Human CD4+ T-Cell Clones Specific forMycobacterium tuberculosis
ABSTRACT Antigen-specific cytolytic CD4+ T lymphocytes controlMycobacterium tuberculosis infection by secreting cytokines and by… 
Highly Cited
2000
Highly Cited
2000
Killer inhibitory receptor (CD158b) modulates the lytic activity of tumor-specific T lymphocytes infiltrating renal cell carcinomas.
In this study, we showed that renal tumors contain substantial subsets of CD8(+) p58(+) T cells. From 1 of these tumors, T cells… 
Highly Cited
1999
Highly Cited
1999
CD28‐negative cytolytic effector T cells frequently express NK receptors and are present at variable proportions in circulating lymphocytes from healthy donors and melanoma patients
In humans, NK receptors are expressed by natural killer cells and some T cells, the latter of which are preferentially α βTCR… 
1999
1999
Using carboxyfluorescein diacetate succinimidyl ester to monitor human NK cell division: Analysis of the effect of activating and inhibitory class I MHC receptors
  • H. Warren
  • Immunology and cell biology
  • 1999
  • Corpus ID: 8754835
Human NK cells labelled intracellularly with the fluorescent dye 5‐ and 6‐carboxyfluorescein diacetate succinimidyl ester (CFSE… 
Highly Cited
1997
Highly Cited
1997
Peptides isolated from HLA-Cw*0304 confer different degrees of protection from natural killer cell-mediated lysis.
HLA class I molecules bind peptides derived from proteins degraded in the cytoplasm and display them for surveillance by the… 
Highly Cited
1997
Highly Cited
1997
Differential association of phosphatases with hematopoietic co‐receptors bearing immunoreceptor tyrosine‐based inhibition motifs
A novel family of inhibitory co‐receptors has been recently defined according to the presence in their intracytoplasmic domain of… 
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