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KIR2DL2 gene

Known as: CD158B1, cl-43, NKAT6 
This gene plays a role in the negative regulation of natural killer cell activity.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
The human killer cell Ig-like receptor (KIR) locus comprises two groups of KIR haplotypes, termed A and B. These are present in… Expand
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Highly Cited
2013
Highly Cited
2013
Human natural killer (NK) cells are functionally regulated by killer cell immunoglobulin-like receptors (KIRs) and their… Expand
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Highly Cited
2011
Highly Cited
2011
To determine the influence of KIR and HLA class I polymorphism on human NK cell repertoires, 32 different clonotypes representing… Expand
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Highly Cited
2009
Highly Cited
2009
Humans and chimpanzees have orthologous MHC class I, but few orthologous killer cell Ig-like receptors (KIR). Most divergent are… Expand
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Highly Cited
2008
Highly Cited
2008
Interactions between HLA-C ligands and inhibitory killer cell Ig-like receptors (KIR) control the development and response of… Expand
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Highly Cited
2004
Highly Cited
2004
The killer immunoglobulin-like receptor (KIR) family recognizes class I major histocompatibility complex (MHC) molecules and… Expand
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Highly Cited
2000
Highly Cited
2000
Target cell lysis is regulated by natural killer (NK) cell receptors that recognize class I MHC molecules. Here we report the… Expand
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Highly Cited
1999
Highly Cited
1999
Killer cell inhibitory receptors (KIR) protect class I HLAs expressing target cells from natural killer (NK) cell-mediated lysis… Expand
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Highly Cited
1998
Highly Cited
1998
Cytotoxicity of human NK cells is under negative control of killer cell Ig-like receptors (KIR) specific for HLA class I. To… Expand
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Highly Cited
1998
Highly Cited
1998
NK cells and T cells express killer cell inhibitory receptors (KIR) recognizing polymorphic MHC class I molecules. Although prior… Expand
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