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KIAA1549 gene
Known as:
KIAA1549/BRAF Fusion Gene
, BRAF/KIAA1549 Fusion Gene
, KIAA1549
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A fusion gene that results from a tandem duplication of approximately 2 Mb at 7q34 which fuses exon 15 or 16 of the KIAA1549 gene to exon 9 or 11 of…
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National Institutes of Health
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Related topics
Related topics
4 relations
BRAF gene
Signal Transduction
Tyrosine Phosphorylation
UPF0606 Protein KIAA1549
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Low-grade glioma subtypes revealed
P. Sidaway
Nature Reviews Clinical Oncology
2020
Corpus ID: 216649658
Nature reviews | CliniCal OnCOlOgy Low-grade gliomas (LGGs) are the most common brain tumours in children and can arise from…
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2019
2019
Detection of the KIAA1549-BRAF fusion gene in cells forming microvascular proliferations in pilocytic astrocytoma
Shinji Yamashita
,
H. Takeshima
,
+9 authors
K. Yokogami
PLoS ONE
2019
Corpus ID: 198171733
Microvascular proliferation (MVP), an aberrant vascular structure containing multilayered mitotically active endothelial- and…
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2018
2018
Homozygous mutations in KIAA1549, encoding a ciliary protein, cause autosomal recessive retinitis pigmentosa.
S. Roosing
,
S. D. Bruijn
,
+4 authors
F. Cremers
2018
Corpus ID: 91657875
2016
2016
Molecular Analysis of Pediatric Oligodendrogliomas Highlights Genetic Differences with Adult Counterparts and Other Pediatric Gliomas
David W. Nauen
,
Lisa M Haley
,
+4 authors
F. Rodriguez
Brain Pathology
2016
Corpus ID: 25236939
Oligodendroglioma represents a distinctive neoplasm in adults but similar neoplasms occur rarely in children. We studied 20 cases…
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2016
2016
LG-47TYPE II RAF INHIBITORS INHIBIT BRAF MUTATIONS AND TRUNCATED FUSIONS IN PEDIATRIC LOW-GRADE GLIOMAS
M. Kieran
,
Yu Sun
,
+23 authors
S. Buhrlage
2016
Corpus ID: 57382915
LG-47. TYPE II RAF INHIBITORS INHIBIT BRAF MUTATIONS AND TRUNCATED FUSIONS IN PEDIATRIC LOW-GRADE GLIOMAS Mark W. Kieran1,2, Yu…
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2015
2015
Adult recurrent pilocytic astrocytoma: Clinical, histopathological and molecular study.
S. Trabelsi
,
N. Mama
,
+10 authors
D. H’mida ben brahim
Neuro-chirurgie
2015
Corpus ID: 21888641
2014
2014
OP32A COMBINED STRATEGY FOR THE DETECTION OF BRAF FUSIONS IN PILOCYTIC ASTROCYTOMA USING RT-PCR AND FISH
Claire L Faulkner
,
Abigail Shaw
,
+6 authors
K. Kurian
2014
Corpus ID: 74099035
INTRODUCTION: Pilocytic astrocytomas (WHO grade I) are the most common paediatric gliomas. The FISH test for KIAA1549-BRAF…
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2013
2013
BRAF alterations in pediatric low grade gliomas and mixed neuronal–glial tumors
E. Dimitriadis
,
G. Alexiou
,
+5 authors
N. Pandis
Journal of Neuro-Oncology
2013
Corpus ID: 24005811
Low grade astrocytomas are the most common brain tumor in children. Recent studies have identified alterations in the BRAF serine…
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2012
2012
Pediatric Low-Grade Astrocytoma Fusion Predicts Better Clinical Outcome in BRAF-KIAA1549
C. Hawkins
,
E. Walker
,
+13 authors
U. Tabori
2012
Corpus ID: 51767616
Purpose: Recent studies have revealed that the majority of pediatric low-grade astrocytomas (PLGA) harbor the BRAF-KIAA1549 (B-K…
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2011
2011
Sensitive Determination of BRAF Copy Number in Clinical Samples by Pyrosequencing
Prashanth Setty
,
M. Gessi
,
+4 authors
A. Waha
Diagnostic molecular pathology (Print)
2011
Corpus ID: 1697990
Pilocytic astrocytoma is the most frequently occurring brain tumor during childhood. It is classified as grade I by the World…
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