Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

KIAA0196 wt Allele

Known as: RTSC, SPG8, Spastic Paraplegia 8 (Autosomal Dominant) Gene 
Human KIAA0196 wild-type allele is located in the vicinity of 8q24.13 and is approximately 68 kb in length. This allele, which encodes WASH complex… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Substantial clinical, pathological, and genetic overlap exists between amyotrophic lateral sclerosis (ALS) and frontotemporal… Expand
2013
2013
SPG8 is a rare autosomal dominant hereditary spastic paraplegia (AD-HSP), with only six SPG8 families described so far. Our… Expand
  • figure 1
  • figure 2
Highly Cited
2007
Highly Cited
2007
Hereditary spastic paraplegia (HSP) is a progressive upper-motor neurodegenerative disease. The eighth HSP locus, SPG8, is on… Expand
  • figure 1
  • table 2
  • figure 2
  • figure 3
  • figure 4
2006
2006
Sir: Hereditary spastic paraplegia (SPG) is clinically heterogeneous with both pure and complicated forms. The complicated forms… Expand
  • figure 1
Highly Cited
2005
Highly Cited
2005
Hereditary spastic paraplegia (HSP) is a genetically heterogeneous group of neurodegenerative disorders characterized by… Expand
  • table 1
  • figure 1
2003
2003
Grosgruppenverfahren bieten neue Moglichkeiten der Gestaltung von Veranderungsprozessen. Sie sind in Deutschland noch relativ… Expand
2002
2002
The purpose of the present study was to determine the major functional, pharmacological, and regulatory properties of the… Expand
1999
1999
Objective: To map the gene responsible for autosomal dominant pure hereditary spastic paraplegia (ADPHSP) in a large affected… Expand
Highly Cited
1988
Highly Cited
1988
High-dose methotrexate (HDMTX, 1,000 mg/m2) and cranial irradiation/sequential chemotherapy (RTSC) were compared for ability to… Expand
Highly Cited
1988
Highly Cited
1988
High-dose methotrexate (HDMTX) added to a basic regimen of chemotherapy proved superior to cranial irradiation and sequentially… Expand
  • table 1
  • table 2