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KH 1060

Known as: 1,3-Cyclohexanediol, 5-((1-(1-((4-ethyl-4-hydroxyhexyl)oxy)ethyl)octahydro-7a-methyl-4H-inden-4-ylidene)ethylidene)-4-methylene-, (1S-(1alpha(S*),3abeta,4E(1S*,3R*,5Z),7aalpha))-, KH-1060, KH1060 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (3)

Antineoplastic AgentsCalcitriolImmunosuppressive Agents
analogs & derivatives

Papers overview

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Highly Cited
2003
Highly Cited
2003
1,25-dihydroxyvitamin D3-induced apoptosis of retinoblastoma cells is associated with reciprocal changes of Bcl-2 and bax.
2003
2003
Inhibition of MG-63 cell cycle progression by synthetic vitamin D3 analogs mediated by p27, Cdk2, cyclin E, and the retinoblastoma protein.
1999
1999
Vitamin D Analogs, 20-Epi-22-Oxa-24a,26a,27a,-Trihomo-1α,25(OH)2-Vitamin D3, 1,24(OH)2-22-Ene-24-Cyclopropyl-Vitamin D3 and 1α,25(OH)2-Lumisterol3 Prime NB4 Leukemia Cells for Monocytic…
Side-chain modified vitamin D analogs including 20-Epi-22-oxa-24a,26a,27a-trihomo-1α,25-dihydroxyvitamin D3 (KH1060), and 1,24… 
1997
1997
The vitamin D analog, KH1060, is rapidly degraded both in vivo and in vitro via several pathways: principal metabolites generated retain significant biological activity.
Vitamin D analogs are valuable drugs with established and potential uses in hyperproliferative disorders. Lexacalcitol (KH1060… 
1997
1997
Interaction of vitamin D derivatives and granulocyte–macrophage colony-stimulating factor in leukaemic cell differentiation
The ability of the physiologically active form of vitamin D, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3) and two novel vitamin D… 
1996
1996
Calcitriol and lexicalcitol (KH1060) inhibit the growth of human breast adenocarcinoma cells by enhancing transforming growth factor-beta production.
1995
1995
The effects of KH 1060, a potent 20‐epi analogue of the vitamin D3 hormone, on hairless mouse skin in vivo
Summary Dermal effects of KH 1060, a novel, highly potent 20‐epi analogue of 1α,25‐dihyroxyvitamin D3, were investigated in a… 
Highly Cited
1994
Highly Cited
1994
All-trans retinoic acid and 1 alpha,25-dihydroxyvitamin D3 co-operate to promote differentiation of the human promyeloid leukemia cell line HL60 to monocytes.
A basis for differentiation therapy of leukemias is provided by knowledge of agents which induce specific lineage maturation. All… 
1993
1993
1,25‐dihydroxyvitamin D3 and the vitamin D analogue KH1060 induce hyperproliferation in normal mouse epidermis
Abstract 1,25‐dihydroxyvitamin D3 (calcitriol) affects differentiation and proliferation of epidermal keratinocytes in vitro and… 
1989
1989
VITAMIN D AND BREAST CANCER
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