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KDM4C gene

Known as: lysine demethylase 4C, KDM4C, GENE AMPLIFIED IN SQUAMOUS CELL CARCINOMA 1 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Reduced Histone H3 Lysine 9 Methylation Contributes to the Pathogenesis of Latent Autoimmune Diabetes in Adults via Regulation of SUV39H2 and KDM4C
Aims. Latent autoimmune diabetes in adults (LADA) is an autoimmune disease of which the mechanism is not clear. Emerging evidence… 
Review
2017
Review
2017
Histone demethylase JMJD2C: epigenetic regulators in tumors
Histone methylation is one of the major epigenetic modifications, and various histone methylases and demethylases participate in… 
2016
2016
Increase in GFAP‐positive astrocytes in histone demethylase GASC1/KDM4C/JMJD2C hypomorphic mutant mice
GASC1, also known as KDM4C/JMJD2C, is a histone demethylase for histone H3 lysine 9 (H3K9) and H3K36. In this study, we observed… 
2016
2016
Post-Transcriptional Regulation of the GASC1 Oncogene with Active Tumor-Targeted siRNA-Nanoparticles.
Basal-like breast cancer (BLBC) accounts for the most aggressive types of breast cancer, marked by high rates of relapse and poor… 
2015
2015
Overexpression of KDM4 lysine demethylases disrupts the integrity of the DNA mismatch repair pathway
The KDM4 family of lysine demethylases consists of five members, KDM4A, -B and -C that demethylate H3K9me2/3 and H3K36me2/3 marks… 
2015
2015
A High-Throughput Mass Spectrometry Assay Coupled with Redox Activity Testing Reduces Artifacts and False Positives in Lysine Demethylase Screening
Demethylation of histones by lysine demethylases (KDMs) plays a critical role in controlling gene transcription. Aberrant… 
2014
2014
Spatiotemporal expression of DNA demethylation enzymes and histone demethylases in bovine embryos.
Abstract Fertilization in bovines causes profound changes in the epigenetic profile that affect both DNA methylation patterns and… 
2014
2014
Natural variation in the histone demethylase, KDM4C, influences expression levels of specific genes including those that affect cell growth
DNA sequence variants influence gene expression and cellular phenotypes. In this study, we focused on natural variation in the… 
2014
2014
GASC1 expression in lung carcinoma is associated with smoking and prognosis of squamous cell carcinoma.
GASC1 (gene amplified in squamous cell carcinoma 1) encodes a nuclear protein that epigenetically catalyses the lysine… 
Highly Cited
2004
Highly Cited
2004
Identification and characterization of JMJD2 family genes in silico.
JMJD1 family genes, including JMJD1 (TSGA), TRIP8, and C5orf7 (5qNCA), encode nuclear proteins with Jumonji C (JmjC), TRI8H1 and… 
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