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KDM4C gene
Known as:
lysine demethylase 4C
, KDM4C
, GENE AMPLIFIED IN SQUAMOUS CELL CARCINOMA 1
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National Institutes of Health
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Papers overview
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Highly Cited
2016
Highly Cited
2016
Targeting Aberrant Epigenetic Networks Mediated by PRMT1 and KDM4C in Acute Myeloid Leukemia
N. Cheung
,
T. Fung
,
+7 authors
C. So
Cancer Cell
2016
Corpus ID: 6800622
Review
2013
Review
2013
KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells.
William L. Berry
,
R. Janknecht
Cancer Research
2013
Corpus ID: 3081573
Lysine methylation is one of the most prominent histone posttranslational modifications that regulate chromatin structure…
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Highly Cited
2012
Highly Cited
2012
IDH mutation impairs histone demethylation and results in a block to cell differentiation
Chao Lu
,
P. Ward
,
+14 authors
C. Thompson
Nature
2012
Corpus ID: 4408713
Recurrent mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 have been identified in gliomas, acute myeloid leukaemias (AML…
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Highly Cited
2012
Highly Cited
2012
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
W. Luo
,
Ryan Chang
,
Jun Zhong
,
A. Pandey
,
G. Semenza
Proceedings of the National Academy of Sciences
2012
Corpus ID: 22422080
Hypoxia-inducible factor 1 (HIF-1) activates transcription of genes encoding proteins that play key roles in breast cancer…
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Highly Cited
2010
Highly Cited
2010
Design, synthesis, enzyme-inhibitory activity, and effect on human cancer cells of a novel series of jumonji domain-containing protein 2 histone demethylase inhibitors.
Shohei Hamada
,
Takayoshi Suzuki
,
+14 authors
N. Miyata
Journal of Medicinal Chemistry
2010
Corpus ID: 7149375
Selective inhibitors of Jumonji domain-containing protein (JMJD) histone demethylases are candidate anticancer agents as well as…
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Highly Cited
2009
Highly Cited
2009
Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer
Gang Liu
,
A. Bollig-Fischer
,
+4 authors
Zeng‐Quan Yang
Oncogene
2009
Corpus ID: 3255493
Earlier, mapping of the 9p23–24 amplicon in esophageal cancer cell lines led us to the positional cloning of gene amplified in…
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Highly Cited
2009
Highly Cited
2009
Genetic associations of 115 polymorphisms with cancers of the upper aerodigestive tract across 10 European countries: the ARCAGE project.
C. Canova
,
M. Hashibe
,
+27 authors
P. Brennan
Cancer Research
2009
Corpus ID: 19152642
Cancers of the upper aerodigestive tract (UADT) include malignant tumors of the oral cavity, pharynx, larynx, and esophagus and…
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Highly Cited
2007
Highly Cited
2007
Cooperative demethylation by JMJD2C and LSD1 promotes androgen receptor-dependent gene expression
Melanie Wissmann
,
N. Yin
,
+9 authors
R. Schüle
Nature Cell Biology
2007
Corpus ID: 26006234
Posttranslational modifications of histones, such as methylation, regulate chromatin structure and gene expression. Recently…
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Highly Cited
2006
Highly Cited
2006
The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3
P. Cloos
,
J. Christensen
,
+5 authors
K. Helin
Nature
2006
Corpus ID: 2874903
Methylation of lysine and arginine residues on histone tails affects chromatin structure and gene transcription. Tri- and…
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Highly Cited
2000
Highly Cited
2000
Identification of a novel gene, GASC1, within an amplicon at 9p23-24 frequently detected in esophageal cancer cell lines.
Z. Q. Yang
,
I. Imoto
,
+6 authors
J. Inazawa
Cancer Research
2000
Corpus ID: 13518970
In a recent study, we identified frequent amplification of DNA copy number at chromosome 9p23-24 in cell lines derived from…
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