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KDM4B gene

Known as: JMJD2B, JUMONJI DOMAIN-CONTAINING PROTEIN 2B, KIAA0876 
National Institutes of Health

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KDM4A gene

Papers overview

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Review
2019
Review
2019
KDM4B: A Nail for Every Hammer?
Epigenetic changes are well-established contributors to cancer progression and normal developmental processes. The reversible… 
Highly Cited
2015
Highly Cited
2015
KDM4/JMJD2 Histone Demethylase Inhibitors Block Prostate Tumor Growth by Suppressing the Expression of AR and BMYB-Regulated Genes.
2015
2015
The emerging role of lysine demethylases in DNA damage response: dissecting the recruitment mode of KDM4D/JMJD2D to DNA damage sites
KDM4D is a lysine demethylase that removes tri- and di- methylated residues from H3K9 and is involved in transcriptional… 
Highly Cited
2013
Highly Cited
2013
The lysine demethylase, KDM4B, is a key molecule in androgen receptor signalling and turnover
The androgen receptor (AR) is a key molecule involved in prostate cancer (PC) development and progression. Post-translational… 
Highly Cited
2013
Highly Cited
2013
Deregulated expression of selected histone methylases and demethylases in prostate carcinoma.
Prostate cancer (PCa), a leading cause of cancer-related morbidity and mortality, arises through the acquisition of genetic and… 
Highly Cited
2012
Highly Cited
2012
Histone demethylases KDM4B and KDM6B promotes osteogenic differentiation of human MSCs.
Highly Cited
2012
Highly Cited
2012
HIF-1α-induced histone demethylase JMJD2B contributes to the malignant phenotype of colorectal cancer cells via an epigenetic mechanism.
Hypoxia-inducible factor 1α (HIF-1α) plays a key role in mediating cancer cell malignant characteristics. Recent studies have… 
Highly Cited
2011
Highly Cited
2011
Histone demethylase JMJD2B coordinates H3K4/H3K9 methylation and promotes hormonally responsive breast carcinogenesis
It is well-documented that the methylation of histone H3 lysine 4 (H3K4) and of H3K9 are mutually exclusive, an epigenetic… 
Highly Cited
2011
Highly Cited
2011
Histone Demethylase JMJD2B Functions as a Co-Factor of Estrogen Receptor in Breast Cancer Proliferation and Mammary Gland Development
Estrogen is a key regulator of normal function of female reproductive system and plays a pivotal role in the development and… 
Highly Cited
2004
Highly Cited
2004
Identification and characterization of JMJD2 family genes in silico.
JMJD1 family genes, including JMJD1 (TSGA), TRIP8, and C5orf7 (5qNCA), encode nuclear proteins with Jumonji C (JmjC), TRI8H1 and… 
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