KDM4A gene

Known as: lysine demethylase 4A, KDM4A, KIAA0677 
 
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Acquired chromosomal instability and copy number alterations are hallmarks of cancer. Enzymes capable of promoting site-specific… (More)
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Review
2013
Review
2013
Lysine methylation is one of the most prominent histone posttranslational modifications that regulate chromatin structure… (More)
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Highly Cited
2012
Highly Cited
2012
In response to DNA damage, cells initiate complex signalling cascades leading to growth arrest and DNA repair. The recruitment of… (More)
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2011
2011
Reversible methylation of lysine residues has emerged as a central mechanism for epigenetic regulation and is a component of the… (More)
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Highly Cited
2011
Highly Cited
2011
Mutations in isocitrate dehydrogenases (IDHs) have a gain-of-function effect leading to R(-)-2-hydroxyglutarate (R-2HG… (More)
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2010
2010
The KDM4/JMJD2 family of histone demethylases is amplified in human cancers. However, little is known about their physiologic or… (More)
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Highly Cited
2007
Highly Cited
2007
Trimethylation of histone H3 on lysine 4 (H3K4me3) localizes near the 5' region of genes and is tightly associated with active… (More)
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2007
2007
The Jumonji C domain is a catalytic motif that mediates histone lysine demethylation. The Jumonji C-containing oxygenase JMJD2A… (More)
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Highly Cited
2006
Highly Cited
2006
Histone methylation regulates chromatin structure, transcription, and epigenetic state of the cell. Histone methylation is… (More)
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Highly Cited
2006
Highly Cited
2006
Post-translational modification of chromatin has profound effects on many biological processes including transcriptional… (More)
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