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KCNQ1OT1 protein, human

Known as: NCRNA00012, KvDMR1 protein, human, Long QT Intronic Transcript 1 
KCNQ1 opposite strand/antisense transcript 1 (~92 kb) is encoded by the human KCNQ1OT1 gene. This non-coding RNA plays a role in epigenetic processes… 
National Institutes of Health

Related topics

Related topics

3 relations
Epigenetic ProcessKCNQ1OT1 gene

Broader (1)

Voltage-Gated Potassium Channel

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2018
Highly Cited
2018
LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling
Numerous findings have demonstrated that long noncoding RNA (lncRNA) dysregulation plays a key role in many human neoplasms… 
Highly Cited
2014
Highly Cited
2014
Long Noncoding RNAs in Patients With Acute Myocardial Infarction
Rationale: Long noncoding RNAs (lncRNAs) constitute a novel class of noncoding RNAs that regulate gene expression. Although… 
Highly Cited
2012
Highly Cited
2012
Defects in imprinting and genome-wide DNA methylation are not common in the in vitro fertilization population.
Highly Cited
2006
Highly Cited
2006
Oocyte growth‐dependent progression of maternal imprinting in mice
In mammals, some genes categorized as imprinted genes are exclusively expressed either from maternal or paternal allele. This… 
Highly Cited
2006
Highly Cited
2006
Epigenetic dynamics of the Kcnq1 imprinted domain in the early embryo
The mouse Kcnq1 imprinted domain is located on distal chromosome 7 and contains several imprinted genes that are paternally… 
Highly Cited
2004
Highly Cited
2004
An Antisense RNA Regulates the Bidirectional Silencing Property of the Kcnq1 Imprinting Control Region
ABSTRACT The Kcnq1 imprinting control region (ICR) located in intron 10 of the Kcnq1 gene is unmethylated on the paternal… 
Highly Cited
2002
Highly Cited
2002
Discordant KCNQ1OT1 imprinting in sets of monozygotic twins discordant for Beckwith-Wiedemann syndrome.
Beckwith-Wiedemann syndrome (BWS) presents with visceromegaly, macroglossia, tumor predisposition and other congenital… 
Highly Cited
2001
Highly Cited
2001
Increased tumour risk for BWS patients correlates with aberrant H19 and not KCNQ1OT1 methylation: occurrence of KCNQ1OT1 hypomethylation in familial cases of BWS.
Beckwith-Wiedemann syndrome (BWS) is an overgrowth malformation syndrome that maps to human chromosome 11p15.5, a region that… 
Highly Cited
2001
Highly Cited
2001
Analysis of the methylation status of the KCNQ1OT and H19 genes in leukocyte DNA for the diagnosis and prognosis of Beckwith–Wiedemann syndrome
Beckwith–Wiedemann syndrome (BWS) is an overgrowth disorder involving developmental abnormalities, tissue and organ hyperplasia… 
Highly Cited
2000
Highly Cited
2000
Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndrome.
Human chromosome 11p15.5 harbors an intriguing imprinted gene cluster of 1 Mb. This imprinted domain is implicated in a wide… 
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