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KCNQ1OT1 gene

Known as: KCNQ1 antisense RNA 2 (non-protein coding), NCRNA00012, KCNQ1 overlapping transcript 1 (non-protein coding) 
This gene plays a role in the epigenetic regulation of gene transcription.
National Institutes of Health

Related topics

Related topics

3 relations
Epigenetic ProcessKCNQ1OT1 protein, humanTranscriptional Regulation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2020
2020
KCNQ1OT1 regulates osteogenic differentiation of hBMSC by miR-320a/Smad5 axis.
OBJECTIVE Osteogenic differentiation plays a crucial role in maintaining general bone homeostasis. Long non-coding RNAs (lncRNAs… 
2019
2019
Effects of LncRNA KCNQ1OT1 on proliferation and migration of ovarian cancer cells by Wnt/β-catenin.
OBJECTIVE To explore the role of long noncoding ribonucleic acid (lncRNA) KCNQ1OT1 in the proliferation, apoptosis, and migration… 
2015
2015
Pyrrole-imidazole polyamide-mediated silencing of KCNQ1OT1 expression induces cell death in Wilms' tumor cells.
KvDMR (an intronic CpG island within the KCNQ1 gene) is one of the imprinting control regions on human chromosome 11p15.5. Since… 
Review
2014
Review
2014
Isolated hypermethylation of GRB10 (7p12.2) in a Silver–Russell syndrome patient carrying a 20p13 microdeletion
To the Editor : Silver–Russell syndrome (SRS; OMIM 180860) is an imprinting disorder characterized by primordial growth… 
2013
2013
Abnormal methylation of KCNQ1OT1 and differential methylation of H19 imprinting control regions in human ICSI embryos.
Summary To evaluate the integrity of genomic imprinting in embryos that failed to develop normally following intracytoplasmic… 
2011
2011
The heterogeneity of hyperinsulinaemic hypoglycaemia in 19 patients with Beckwith-Wiedemann syndrome due to KvDMR1 hypomethylation
Abstract Beckwith-Wiedemann syndrome (BWS) is an overgrowth syndrome caused by multiple epigenetic and genetic changes affecting… 
2011
2011
MIRA-SNuPE, a quantitative, multiplex method for measuring allele-specific DNA methylation
5-methyl-C (5mC) and 5-hydroxymethyl-C (5hmC) are epigenetic marks with well known and putative roles in gene regulation… 
Highly Cited
2010
Highly Cited
2010
Aberrant CpG methylation of the imprinting control region KvDMR1 detected in assisted reproductive technology-produced calves and pathogenesis of large offspring syndrome.
2008
2008
Epimutations of the KCNQ1OT1 imprinting center of chromosome 11 in early human embryolethality
Disturbance of the epigenetic status of the H19 and KCNQ1OT1 imprinting centers of chromosome 11 and the CDKN1C imprinted gene in… 
2003
2003
Silencing of CDKN 1 C ( p 57 KIP 2 ) is associated with hypomethylation at KvDMR 1 in Beckwith – Wiedemann syndrome
Context: Beckwith–Wiedemann syndrome (BWS) arises by several genetic and epigenetic mechanisms affecting the balance of imprinted… 
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