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JNK Pathway

Known as: JNK signalling pathway, JNK Pathways, Pathway, JNK Signaling 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

stress-activated protein kinase signaling cascade

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
PPAR-gamma ligands up-regulate basic fibroblast growth factor-induced VEGF release through amplifying SAPK/JNK activation in osteoblasts.
2005
2005
SAPK/JNK plays a role in transforming growth factor-beta-induced VEGF synthesis in osteoblasts.
We previously reported that transforming growth factor-beta (TGF-beta) activates p44/p42 mitogen-activated protein (MAP) kinase… 
Highly Cited
2003
Highly Cited
2003
Bcl-w is expressed in a majority of infiltrative gastric adenocarcinomas and suppresses the cancer cell death by blocking stress-activated protein kinase/c-Jun NH2-terminal kinase activation.
To determine a cellular factor supporting the survival of gastric cancer cells, a comparative study was performed using two human… 
Highly Cited
2003
Highly Cited
2003
Involvement of SAPK/JNK in basic fibroblast growth factor-induced vascular endothelial growth factor release in osteoblasts.
We previously reported that basic fibroblast growth factor (FGF-2) activates p44/p42 mitogen-activated protein (MAP) kinase… 
Review
2003
Review
2003
Induction of apoptosis through the activation of SAPK/JNK followed by the expression of death receptor Fas in X-irradiated cells.
A post-irradiation treatment of the human leukemia cell line MOLT-4 with the antioxidant Trolox attenuated caspase-3 dependent… 
Highly Cited
2001
Highly Cited
2001
Adaptive concentrations of hydrogen peroxide suppress cell death by blocking the activation of SAPK/JNK pathway.
Low levels of H2O2 can induce cellular resistance to subsequent higher levels of H2O2. By using human U937 leukemia cells, it was… 
1999
1999
Effects of intracellular calcium chelator BAPTA-AM on radiation-induced apoptosis regulated by activation of SAPK/JNK and caspase-3 in MOLT-4 cells.
PURPOSE To examine the roles ofintracellular calcium in radiation-induced apoptosis of MOLT-4 cells, the effects of intracellular… 
Highly Cited
1999
Highly Cited
1999
Human DU145 prostate cancer cells overexpressing mitogen-activated protein kinase phosphatase-1 are resistant to Fas ligand-induced mitochondrial perturbations and cellular apoptosis
Recent studies have suggested that MAP kinase phosphatase 1 (MKP-1) is overexpressed in prostate cancer. To evaluate the role of… 
Highly Cited
1998
Highly Cited
1998
The PEA3 Ets transcription factor is a downstream target of the HER2/Neu receptor tyrosine kinase
The HER2/neu gene, which is overexpressed in 20 – 30% of human breast tumors, encodes a receptor tyrosine kinase that functions… 
Highly Cited
1997
Highly Cited
1997
Discordant Activation of Stress-activated Protein Kinases or c-Jun NH2-terminal Protein Kinases in Tissues of Heat-stressed Mice*
Stress-activated protein kinases (SAPK) or c-Jun NH2-terminal protein kinases (JNK) are believed to be crucial signal transducers… 
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