JNJ-42756493

Known as: pan-FGFR Tyrosine Kinase Inhibitor JNJ-42756493 
An orally bioavailable, pan fibroblast growth factor receptor (FGFR) inhibitor with potential antineoplastic activity. Upon oral administration, JNJ… (More)

Topic mentions per year

Topic mentions per year

2015-2017
02420152017

Papers overview

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2017
2017
Fibroblast growth factor (FGF) signaling plays critical roles in key biological processes ranging from embryogenesis to wound… (More)
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2017
2017
Fibroblast growth factor receptor (FGFR) genetic alterations are frequently observed in cancer, suggesting that FGFR inhibition… (More)
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Review
2017
Review
2017
Fibroblast growth factor receptor (FGFR) genetic alterations are frequently observed in cancer, suggesting that FGFR inhibition… (More)
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2017
2017
Introduction This phase 1, open-label, multicenter, single-arm, dose-escalation study aimed to evaluate safety, pharmacokinetics… (More)
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Review
2016
Review
2016
Fibroblast growth factor (FGF)2, FGF4, FGF7 and FGF20 are representative paracrine FGFs binding to heparan-sulfate proteoglycan… (More)
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2015
2015
PURPOSE JNJ-42756493 is an orally administered pan-fibroblast growth factor receptor (FGFR) tyrosine kinase inhibitor. This first… (More)
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2015
2015
We examined the anti-tumor effect and radiosensitizing potential of a small molecule inhibitor of fibroblast growth factor… (More)
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2015
2015
PURPOSE Oncogenic fusions consisting of fibroblast growth factor receptor (FGFR) and TACC are present in a subgroup of… (More)
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2015
2015
Fibroblast growth factor (FGF) and fibroblast growth factor receptor (FGFR) are important regulators of a variety of biologic… (More)
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Review
2015
Review
2015
Fibroblast growth factor receptor (FGFR) signaling is involved in multiple biological processes, including cell proliferation… (More)
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