Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

JNJ-40346527

Known as: FMS Inhibitor JNJ-40346527 
A small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; FMS) with potential antineoplastic activity. FMS… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
Microglia have been implicated in amyloid beta-induced neuropathology, but their role in tau-induced neurodegeneration remains… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
2019
2019
Background & aims Originally believed to be primarily a disorder of T-cell signaling, evidence shows that macrophage-lineage… Expand
  • figure 1
  • figure 2
  • figure 4
  • figure 5
  • figure 6
Review
2018
Review
2018
Colony stimulating factor-1 (CSF-1) is one of the most common proinflammatory cytokine responsible for various inflammatory… Expand
2016
2016
In the present work we show that multiple lung cancer cell lines contain cisplatin resistant cell subpopulations expressing the… Expand
  • table 1
  • figure 1
  • table 2
  • figure 2
  • figure 3
2015
2015
Purpose: This phase I/II study investigated JNJ-40346527, a selective inhibitor of the colony-stimulating factor-1 receptor (CSF… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • table 3
2015
2015
Objective. To assess the efficacy and safety of JNJ-40346527, a selective inhibitor of colony-stimulating factor-1 (CSF-1… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
  • figure 2
2014
2014
Background JNJ-40346527, an investigational agent, is a selective inhibitor of the colony stimulating factor-1 receptor (CSF-1R… Expand
Review
2013
Review
2013
Introduction JNJ-40346527 is a selective inhibitor of the colony stimulating factor-1 receptor (CSF-1R) tyrosine kinase. It… Expand