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Ivermectin

Known as: Ivermectin [Chemical/Ingredient], Ivermectina, Ivermectinum 
A macrocyclic lactone derived from Streptomyces avermitilis with antiparasitic activity. Ivermectin exerts its anthelmintic effect via activating… 
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (16)

6,8a-seco-6,8a-deoxyavermectin B1a aglyconeDuraMectinMectizanParid
Antiparasitic AgentsAscariasisEnterobiasisIn Blood

Broader (1)

Insecticides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2011
Review
2011
Ivermectin, ‘Wonder drug’ from Japan: the human use perspective
Discovered in the late-1970s, the pioneering drug ivermectin, a dihydro derivative of avermectin—originating solely from a single… 
Highly Cited
2011
Highly Cited
2011
Principles of activation and permeation in an anion-selective Cys-loop receptor
Fast inhibitory neurotransmission is essential for nervous system function and is mediated by binding of inhibitory… 
Highly Cited
2010
Highly Cited
2010
Oral ivermectin versus malathion lotion for difficult-to-treat head lice.
BACKGROUND Head-lice infestation is prevalent worldwide, especially in children 3 to 11 years old. Topical insecticides (i.e… 
Review
2006
Review
2006
Scabies: a ubiquitous neglected skin disease.
Review
2004
Review
2004
The life and times of ivermectin — a success story
Since its introduction more than 20 years ago, ivermectin has proved to be one of the most successful therapeutic drugs in… 
Highly Cited
2001
Highly Cited
2001
Ivermectin, an Unconventional Agonist of the Glycine Receptor Chloride Channel*
The effects of the antihelmintic, ivermectin, were investigated in recombinantly expressed human α1 homomeric and α1β heteromeric… 
Highly Cited
2000
Highly Cited
2000
The genetics of ivermectin resistance in Caenorhabditis elegans.
The ability of organisms to evolve resistance threatens the effectiveness of every antibiotic drug. We show that in the nematode… 
Highly Cited
1997
Highly Cited
1997
avr‐15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans
Ivermectin is a widely used anthelmintic drug whose nematocidal mechanism is incompletely understood. We have used Caenorhabditis… 
Review
1994
Review
1994
Ivermectin in human medicine.
Ivermectin is a potent macro-cyclic lactone causing paralysis in many nematodes and arthropods through an influx of chloride ions… 
Review
1984
Review
1984
Ivermectin: a review of efficacy and safety.
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