Ivermectin

Known as: Ivermectin [Chemical/Ingredient], Ivermectina, Ivermectinum 
A macrocyclic lactone derived from Streptomyces avermitilis with antiparasitic activity. Ivermectin exerts its anthelmintic effect via activating… (More)
National Institutes of Health

Related topics

Related topics

43 relations

Narrower (16)

6,8a-seco-6,8a-deoxyavermectin B1a aglyconeMK-933MectizanParid
(More)
Antiparasitic AgentsAscariasisElephantiasisEnterobiasis
(More)

Broader (1)

Insecticides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Principles of activation and permeation in an anion-selective Cys-loop receptor
Fast inhibitory neurotransmission is essential for nervous system function and is mediated by binding of inhibitory… (More)
  • figure 1
  • figure 2
  • figure 4
  • figure 3
  • figure 5
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Phenotypic Evidence of Emerging Ivermectin Resistance in Onchocerca volvulus
BACKGROUND Ivermectin (IVM) has been used in Ghana for over two decades for onchocerciasis control. In recent years there have… (More)
  • figure 1
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
Review
2008
Review
2008
Ivermectin: 25 years and still going strong.
Ivermectin is a drug that many people will never have heard of. Yet thousands of villagers of all ages in communities scattered… (More)
Is this relevant?
Review
2005
Review
2005
Ivermectin: pharmacology and application in dermatology.
Ivermectin is a synthetic derivative of the antiparasitic class of compounds known as avermectins. It is a macrolide endectocide… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene.
A subpopulation of collie dogs is extremely sensitive to neurotoxicity induced by ivermectin. The aim of this study was to… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
Ivermectin, an unconventional agonist of the glycine receptor chloride channel.
The effects of the antihelmintic, ivermectin, were investigated in recombinantly expressed human alpha(1) homomeric and alpha(1… (More)
  • figure 1
  • figure 2
  • table I
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2000
Highly Cited
2000
The genetics of ivermectin resistance in Caenorhabditis elegans.
The ability of organisms to evolve resistance threatens the effectiveness of every antibiotic drug. We show that in the nematode… (More)
  • table 1
  • figure 1
  • table 3
  • table 2
  • table 4
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Ivermectin: a positive allosteric effector of the alpha7 neuronal nicotinic acetylcholine receptor.
We report that preapplication of ivermectin, in the micromolar range, strongly enhances the subsequent acetylcholine-evoked… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans.
Ivermectin is a widely used anthelmintic drug whose nematocidal mechanism is incompletely understood. We have used Caenorhabditis… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1983
Highly Cited
1983
Ivermectin: a potent new antiparasitic agent.
Ivermectin is the 22,23-dihydro derivative of avermectin B1, a macrocyclic lactone produced by an actinomycete, Streptomyces… (More)
Is this relevant?