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Ivermectin

Known as: Ivermectin [Chemical/Ingredient], Ivermectina, Ivermectinum 
A macrocyclic lactone derived from Streptomyces avermitilis with antiparasitic activity. Ivermectin exerts its anthelmintic effect via activating… 
National Institutes of Health

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Narrower (16)

6,8a-seco-6,8a-deoxyavermectin B1a aglyconeDuraMectinMectizanParid
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Antiparasitic AgentsAscariasisEnterobiasisIn Blood
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Broader (1)

Insecticides

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
Review
2012
Review
2012
An inconvenient truth: global worming and anthelmintic resistance.
Highly Cited
2004
Highly Cited
2004
First documentation of in vivo and in vitro ivermectin resistance in Sarcoptes scabiei.
Ivermectin is increasingly being used to treat scabies, especially crusted (Norwegian) scabies. However, treatment failures… 
Highly Cited
2002
Highly Cited
2002
Safety, Tolerability, and Pharmacokinetics of Escalating High Doses of Ivermectin in Healthy Adult Subjects
Safety and pharmacokinetics (PK) of the antiparasitic drug ivermectin, administered in higher and/or more frequent doses than… 
Highly Cited
2001
Highly Cited
2001
Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene.
A subpopulation of collie dogs is extremely sensitive to neurotoxicity induced by ivermectin. The aim of this study was to… 
Highly Cited
2000
Highly Cited
2000
The genetics of ivermectin resistance in Caenorhabditis elegans.
The ability of organisms to evolve resistance threatens the effectiveness of every antibiotic drug. We show that in the nematode… 
Highly Cited
1994
Highly Cited
1994
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
Review
1989
Review
1989
Ivermectin and Abamectin
Ivermectin and abamectin, members of the avermectin family of compounds, were introduced to the market in the 1980's as a… 
Highly Cited
1987
Highly Cited
1987
Environmental consequences of treating cattle with the antiparasitic drug ivermectin
Ivermectin (22,23-dihydroavermectin B1) is a recently discovered, persistent, broad-spectrum, antiparasitic drug of unpredecented… 
Highly Cited
1983
Highly Cited
1983
Ivermectin: a potent new antiparasitic agent.
Ivermectin is the 22,23-dihydro derivative of avermectin B1, a macrocyclic lactone produced by an actinomycete, Streptomyces… 
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