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Ivermectin
Known as:
Ivermectin [Chemical/Ingredient]
, Ivermectina
, Ivermectinum
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A macrocyclic lactone derived from Streptomyces avermitilis with antiparasitic activity. Ivermectin exerts its anthelmintic effect via activating…
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National Institutes of Health
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Related topics
Related topics
43 relations
Narrower (16)
6,8a-seco-6,8a-deoxyavermectin B1a aglycone
DuraMectin
Mectizan
Parid
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Antiparasitic Agents
Ascariasis
Enterobiasis
In Blood
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Broader (1)
Insecticides
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2020
Highly Cited
2020
The FDA-approved drug ivermectin inhibits the replication of SARS-CoV-2 in vitro
L. Caly
,
J. Druce
,
M. Catton
,
D. Jans
,
K. Wagstaff
Antiviral Research
2020
Corpus ID: 214807042
Review
2012
Review
2012
An inconvenient truth: global worming and anthelmintic resistance.
R. Kaplan
,
A. Vidyashankar
Veterinary parasitology
2012
Corpus ID: 11124687
Highly Cited
2004
Highly Cited
2004
First documentation of in vivo and in vitro ivermectin resistance in Sarcoptes scabiei.
B. Currie
,
Pearly Harumal
,
M. McKinnon
,
Shelley F. Walton
Clinical infectious diseases : an official…
2004
Corpus ID: 12789066
Ivermectin is increasingly being used to treat scabies, especially crusted (Norwegian) scabies. However, treatment failures…
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Highly Cited
2002
Highly Cited
2002
Safety, Tolerability, and Pharmacokinetics of Escalating High Doses of Ivermectin in Healthy Adult Subjects
C. Guzzo
,
C. Furtek
,
+6 authors
K. Lasseter
Journal of clinical pharmacology
2002
Corpus ID: 40836084
Safety and pharmacokinetics (PK) of the antiparasitic drug ivermectin, administered in higher and/or more frequent doses than…
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Highly Cited
2001
Highly Cited
2001
Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene.
K. Mealey
,
S. A. Bentjen
,
J. Gay
,
G. Cantor
Pharmacogenetics
2001
Corpus ID: 37001657
A subpopulation of collie dogs is extremely sensitive to neurotoxicity induced by ivermectin. The aim of this study was to…
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Highly Cited
2000
Highly Cited
2000
The genetics of ivermectin resistance in Caenorhabditis elegans.
J. Dent
,
M. Smith
,
D. Vassilatis
,
L. Avery
Proceedings of the National Academy of Sciences…
2000
Corpus ID: 1887312
The ability of organisms to evolve resistance threatens the effectiveness of every antibiotic drug. We show that in the nematode…
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Highly Cited
1994
Highly Cited
1994
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
A. Schinkel
,
J. Smit
,
+9 authors
P. Borst
Cell
1994
Corpus ID: 29614708
Review
1989
Review
1989
Ivermectin and Abamectin
W. Campbell
Springer New York
1989
Corpus ID: 31916801
Ivermectin and abamectin, members of the avermectin family of compounds, were introduced to the market in the 1980's as a…
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Highly Cited
1987
Highly Cited
1987
Environmental consequences of treating cattle with the antiparasitic drug ivermectin
R. Wall
,
L. Strong
Nature
1987
Corpus ID: 4357835
Ivermectin (22,23-dihydroavermectin B1) is a recently discovered, persistent, broad-spectrum, antiparasitic drug of unpredecented…
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Highly Cited
1983
Highly Cited
1983
Ivermectin: a potent new antiparasitic agent.
W. Campbell
,
M. Fisher
,
E. Stapley
,
G. Albers-Schönberg
,
T. A. Jacob
Science
1983
Corpus ID: 5722439
Ivermectin is the 22,23-dihydro derivative of avermectin B1, a macrocyclic lactone produced by an actinomycete, Streptomyces…
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