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Melioidosis: Epidemiology, Pathophysiology, and Management
Melioidosis is a disease of public health importance in southeast Asia and northern Australia that is associated with high case-fatality rates in animals and humans, and the role of preventative measures, earlier clinical identification, and better management of severe sepsis are required to reduce the burden of this disease. Expand
The Epidemiology and Clinical Spectrum of Melioidosis: 540 Cases from the 20 Year Darwin Prospective Study
Melioidosis should be seen as an opportunistic infection that is unlikely to kill a healthy person, provided infection is diagnosed early and resources are available to provide appropriate antibiotics and critical care. Expand
Endemic melioidosis in tropical northern Australia: a 10-year prospective study and review of the literature.
Intensive therapy with ceftazidime or carbapenems, followed by at least 3 months of eradication therapy with trimethoprim-sulfamethoxazole, was associated with decreased mortality. Expand
Melioidosis: evolving concepts in epidemiology, pathogenesis, and treatment.
  • B. Currie
  • Medicine
  • Seminars in respiratory and critical care…
  • 2 February 2015
While biothreat research is directed toward potential aerosol exposure to B. pseudomallei, the overall proportion of melioidosis cases resulting from inhalation rather than from percutaneous inoculation remains entirely uncertain, although the epidemiology supports a shift to inhalation during severe weather events such as cyclones and typhoons. Expand
Scabies: a ubiquitous neglected skin disease.
This article reviews scabies management strategies in developed countries and resource-poor communities as well as typical complications, including the emergence of resistance and drug-related adverse events, and newer treatments such as ivermectin are also discussed. Expand
The global distribution of Burkholderia pseudomallei and melioidosis: an update.
Some of the factors that are critical to further elucidating the global distribution of Burkholderia pseudomallei and melioidosis include improved access to diagnostic laboratory facilities and formal confirmation of the identity of bacterial isolates from suspected cases. Expand
Genetic epidemiology of Sarcoptes scabiei (Acari: Sarcoptidae) in northern Australia.
Previous data that gene flow between scabies mite populations on human and dog hosts is extremely rare in northern Australia clearly support the previous contention that control programs for human scabies in endemic areas with sympatric S. canis populations must focus on human-to-human transmission. Expand
Problems in Diagnosing Scabies, a Global Disease in Human and Animal Populations
Early identification of disease will enable selective treatment of those affected, reduce transmission and the requirement for mass treatment, limit the potential for escalating mite resistance, and provide another means of controlling scabies in populations in areas of endemicity. Expand
Ethics in Aboriginal research
Ross River virus and Barmah Forest virus infections: a review of history, ecology, and predictive models, with implications for tropical northern Australia.
It is predicted that the exacerbation of current greenhouse conditions will result in longer periods of high mosquito activity in the tropical regions where RRV and BFV are already common, and epidemics may become more frequent in those areas. Expand