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Isovaleryl-CoA dehydrogenase

Known as: Isovaleryl CoA Dehydrogenase, Isovaleryl-Coenzyme A Dehydrogenase, CoA Dehydrogenase, Isovaleryl 
A mitochondrial flavoprotein, this enzyme catalyzes the oxidation of 3-methylbutanoyl-CoA to 3-methylbut-2-enoyl-CoA using FAD as a cofactor. Defects… Expand
National Institutes of Health

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IVD geneIn BloodProcess of secretionantagonists & inhibitors
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Isovaleryl-CoA dehydrogenase deficiency

Papers overview

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Highly Cited
2010
Highly Cited
2010
Identification of the 2-Hydroxyglutarate and Isovaleryl-CoA Dehydrogenases as Alternative Electron Donors Linking Lysine Catabolism to the Electron Transport Chain of Arabidopsis Mitochondria[W][OA]
This study indicates that Lys catabolism can directly channel electrons to the mitochondrial electron transport chain in addition… Expand
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Highly Cited
2009
Highly Cited
2009
Acyl-CoA Dehydrogenases: Dynamic History of Protein Family Evolution
The acyl-CoA dehydrogenases (ACADs) are enzymes that catalyze the α,β-dehydrogenation of acyl-CoA esters in fatty acid and amino… Expand
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Highly Cited
2004
Highly Cited
2004
Shikonins, Phytocompounds from Lithospermum erythrorhizon, Inhibit the Transcriptional Activation of Human Tumor Necrosis Factor α Promoter in Vivo*
Tumor necrosis factor α (TNF-α) contributes to the pathogenesis of both acute and chronic inflammatory diseases and has been a… Expand
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Highly Cited
2004
Highly Cited
2004
Biosynthesis of volatiles by the myxobacterium Myxococcus xanthus.
The volatiles emitted from cell cultures of myxobacterium Myxococcus xanthus were collected by use of a closed-loop stripping… Expand
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Highly Cited
2001
Highly Cited
2001
The mitochondrial isovaleryl-coenzyme a dehydrogenase of arabidopsis oxidizes intermediates of leucine and valine catabolism.
We recently identified a cDNA encoding a putative isovaleryl-coenzyme A (CoA) dehydrogenase in Arabidopsis (AtIVD). In animals… Expand
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2001
2001
Diverse chalcone synthase superfamily enzymes from the most primitive vascular plant, Psilotum nudum
Abstract.Psilotum nudum Griseb is a pteridophyte and belongs to the single family (Psilotaceae) of the division, Psilophyta… Expand
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1997
1997
Structure of human isovaleryl-CoA dehydrogenase at 2.6 A resolution: structural basis for substrate specificity,.
Isovaleryl-CoA dehydrogenase (IVD) belongs to an important flavoprotein family of acyl-CoA dehydrogenases that catalyze the alpha… Expand
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Highly Cited
1989
Highly Cited
1989
Phosphotransbutyrylase from Clostridium acetobutylicum ATCC 824 and its role in acidogenesis.
Phosphotransbutyrylase (phosphate butyryltransferase [EC 2.3.1.19]) from Clostridium acetobutylicum ATCC 824 was purified… Expand
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1987
1987
Purification and properties of short chain acyl-CoA, medium chain acyl-CoA, and isovaleryl-CoA dehydrogenases from human liver.
Short chain acyl-CoA (SCA), medium chain acyl-CoA (MCA), and isovaleryl-CoA (IV) dehydrogenases were purified to homogeneity from… Expand
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Highly Cited
1985
Highly Cited
1985
Fluorometric assay of acyl-CoA dehydrogenases in normal and mutant human fibroblasts.
A fluorimetric, ETF-linked procedure to determine activities of acyl-CoA dehydrogenase in cultured human fibroblasts is described… Expand
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