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Isosorbide Mononitrate

Known as: mononitrate isosorbide, 5-ISMN, isosorbide 5 mononitrate 
The mononitrate salt form of isosorbide, an organic nitrate with vasodilator activity. Isosorbide mononitrate relaxes vascular smooth muscle by… 
National Institutes of Health

Related topics

Related topics

28 relations
24 HR Isosorbide Mononitrate 60 MG Extended Release Oral Tablet24 HR Isosorbide Mononitrate 60 MG Extended Release Oral Tablet [Imdur]AnemiaAngina Pectoris

Narrower (6)

5-ISMN DurulesImdurIsmoMonizid

Broader (3)

Isosorbide DinitrateNitric Oxide DonorsVasodilator Agents

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1993
1993
Factorial design-based optimization of the formulation of isosorbide-5-mononitrate microcapsules.
Sustained action Isosorbide-5-mononitrate (IS-5-MN) microcapsules are prepared in order to overcome the tolerance developed in… 
1988
1988
Mechanisms for the in vivo antiplatelet effects of isosorbide dinitrate.
We investigated two possible reasons for the greater antiplatelet efficacy of isosorbide dinitrate (ISDN) in vivo as compared to… 
Review
1987
Review
1987
Overview of the Pharmacokinetics of Isosorbide-5-Mononitrate
One of the problems of prophylactic antianginal therapy with organic nitrates is without doubt their high first pass effect after… 
1985
1985
A Double-Blind Cross-Over Study on the Effectiveness and Possible Development of Tolerance during Long-Term Therapy with Isosorbide-5-Mononitrate or Isosorbide Dinitrate Slow-Release in Coronary…
It is well known that all types of nitrates are effective in angina pectoris syndrome. However, nearly 100-year old reports… 
1985
1985
Isosorbide-5-mononitrate--effective monotherapy in chronic stable angina.
Isosorbide-5-mononitrate (ISMN) is not subject to first-pass metabolism and has more predictable blood concentrations than… 
1985
1985
Effects of Isosorbide-5-Mononitrate on Hemodynamic Parameters and on Regional Myocardial Ischemia in Conscious Dogs
Isosorbide dinitrate (ISDN) is rapidly metabolized to isosorbide-5-mononitrate (IS-5-MN) and isosorbide-2-mononitrate (IS-2-MN… 
1984
1984
[Prevention of the development of tolerance to isosorbide dinitrate in interval therapy].
A number of carefully controlled studies in recent years have unequivocally documented evidence of tolerance development with… 
1984
1984
[Development of tolerance with regard to the anti-ischemic effect of isosorbide dinitrate in regular multiple daily administration].
In previous studies it had been shown that during longterm treatment of coronary artery disease with isosorbide dinitrate (ISDN… 
1983
1983
An open, long-term, multi-centre study of the anti-anginal efficacy and safety of isosorbide 5-mononitrate at low doses in patients with coronary heart disease.
A total of 250 patients with coronary heart disease diagnosed clinically, by ECG and in some cases by coronary angiography, was… 
1983
1983
Pharmacokinetics of isosorbide-5-mononitrate after oral and intravenous administration in patients with liver cirrhosis: first results.
The pharmacokinetics and bioavailability of IS-5-MN after single-dose oral and intravenous application were investigated over 24…