Skip to search formSkip to main contentSkip to account menu

Isoflurophate

Known as: Diisopropoxyphosphoryl Fluoride, Diisopropylphosphorofluoridate, Phosphorofluoridic acid, bis(1-methylethyl) ester 
A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.
National Institutes of Health

Related topics

Related topics

19 relations

Broader (3)

Cholinesterase InhibitorsProtease Inhibitorsalkylphosphate
Drug AllergyGlaucomaIn BloodParasympathomimetic Agents

Narrower (3)

DyflosFloroprylmipafox

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1979
Highly Cited
1979
PURIFICATION AND PROPERTIES OF A PROLYL ENDOPEPTIDASE FROM RABBIT BRAIN
Abstract— An enzyme with the specificity of a prolyl endopeptidase was purified about 880‐fold from rabbit brain. The enzyme… 
Highly Cited
1976
Highly Cited
1976
Postnatal development of acetylcholinesterase in the caudate-putamen nucleus and substantia nigra of rats
Highly Cited
1974
Highly Cited
1974
PROPERTIES OF PLASMINOGEN ACTIVATORS FORMED BY NEOPLASTIC HUMAN CELL CULTURES
A series of human cell lines has been examined for fibrinolysis in culture. The sera that are activating for fibrinolysis by… 
Highly Cited
1974
Highly Cited
1974
A specific collagenase from rabbit fibroblasts in monolayer culture.
1. Explants of rabbit skin and synovium in tissue culture secreted a specific collagenase into their culture media. Primary… 
Highly Cited
1972
Highly Cited
1972
[10] Enzymatic hydrolysis with carboxypeptidases.
Highly Cited
1966
Highly Cited
1966
Measurement of the affinity and phosphorylation constants governing irreversible inhibition of cholinesterases by di-isopropyl phosphorofluoridate.
1. A procedure is described for determining the affinity constant K(a) and the phosphorylation constant k(p) for the inhibition… 
Highly Cited
1964
Highly Cited
1964
INHIBITION OF CHYMOTRYPSIN ACTIVITY IN CRYSTALLINE TRYPSIN PREPARATIONS.
Investigations of protein structures have made extensive use of trypsin to obtain specific cleavage of the peptide chains at the… 
Highly Cited
1953
Highly Cited
1953
Photo-oxidation of crystalline chymotrypsin in the presence of methylene blue.
Highly Cited
1949
Highly Cited
1949
The measurement of the cytochrome oxidase activity of enzyme preparations.
containing 1 ml. 15 % glycerol solution, 1-0 ml. 0-1 M-sodium acetate, 0-5 ml. 0-3 M-bicarbonate solution and 0 5 ml. of the… 
Highly Cited
1949
Highly Cited
1949
Inhibition of the proteinase and esterase activities of trypsin and chymotrypsin by diisopropyl fluorophosphate; crystallization of inhibited chymotrypsin.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)