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Isoflurophate

Known as: Diisopropoxyphosphoryl Fluoride, Diisopropylphosphorofluoridate, Phosphorofluoridic acid, bis(1-methylethyl) ester 
A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.
National Institutes of Health

Related topics

Related topics

19 relations

Broader (3)

Cholinesterase InhibitorsProtease Inhibitorsalkylphosphate
Drug AllergyGlaucomaIn BloodParasympathomimetic Agents

Narrower (3)

DyflosFloroprylmipafox

Papers overview

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Highly Cited
1993
Highly Cited
1993
Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor.
Thrombin has been implicated in the stimulation of smooth muscle cell (SMC) proliferation that contributes to post angioplasty… 
Review
1989
Review
1989
Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors.
The serine protease family of enzymes is one of the most widely studied group of enzymes, as evidenced by the fact that more… 
Highly Cited
1987
Highly Cited
1987
Purified cytochrome b from human granulocyte plasma membrane is comprised of two polypeptides with relative molecular weights of 91,000 and 22,000.
A new method has been developed for purification of cytochrome b from stimulated human granulocytes offering the advantage of… 
Highly Cited
1985
Highly Cited
1985
In Vivo Regulation of [3H]Acetylcholine Recognition Sites in Brain by Nicotinic Cholinergic Drugs
Abstract: The in vivo regulation of [3H]acetylcholine ([3H]ACh) recognition sites on nicotinic receptors in rat ‐ brain was… 
Highly Cited
1984
Highly Cited
1984
Demonstration of a fast-acting inhibitor of plasminogen activators in human plasma.
This report describes a plasmatic, fast-acting, specific inhibitor (antiactivator) of tissue-type plasminogen activator (t-PA… 
Highly Cited
1981
Highly Cited
1981
A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid).
Highly Cited
1974
Highly Cited
1974
SECRETION OF PLASMINOGEN ACTIVATOR BY STIMULATED MACROPHAGES
Cultured thioglycollate-stimulated peritoneal macrophages synthesize, accumulate, and continuously release high levels of… 
Highly Cited
1973
Highly Cited
1973
ACTIVATION OF HAGEMAN FACTOR IN SOLID AND FLUID PHASES
The activation of Hageman factor in solid and fluid phase has been analyzed. Activation of highly purified Hageman factor… 
Highly Cited
1964
Highly Cited
1964
THE LOCALIZATION OF CHOLINESTERASE ACTIVITY IN RAT CARDIAC MUSCLE BY ELECTRON MICROSCOPY
A method has been developed for localizing sites of cholinesterase activity in rat cardiac muscle by electron microscopy. The… 
Highly Cited
1961
Highly Cited
1961
Leukokinetic studies. IV. The total blood, circulating and marginal granulocyte pools and the granulocyte turnover rate in normal subjects.
When granulocytes are labeled with diisopropyl-fluorophosphate (DFP32) and then returned to the circulation of the donor, the… 
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