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Isoflurophate
Known as:
Diisopropoxyphosphoryl Fluoride
, Diisopropylphosphorofluoridate
, Phosphorofluoridic acid, bis(1-methylethyl) ester
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A di-isopropyl-fluorophosphate which is an irreversible cholinesterase inhibitor used to investigate the NERVOUS SYSTEM.
National Institutes of Health
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Related topics
Related topics
19 relations
Broader (3)
Cholinesterase Inhibitors
Protease Inhibitors
alkylphosphate
Drug Allergy
Glaucoma
In Blood
Parasympathomimetic Agents
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Narrower (3)
Dyflos
Floropryl
mipafox
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1987
Highly Cited
1987
Identification of regions of alpha-thrombin involved in its interaction with hirudin.
S. Stone
,
Paul J. Braun
,
J. Hofsteenge
Biochemistry
1987
Corpus ID: 25823514
The contributions of various regions of human alpha-thrombin to the formation of the tight complex with hirudin have been…
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Highly Cited
1979
Highly Cited
1979
Characterization of "thyroliberin-deamidating enzyme" as a post-proline-cleaving enzyme. Partial purification and enzyme-chemical analysis of the enzyme from anterior pituitary tissue.
H. Knisatschek
,
K. Bauer
Journal of Biological Chemistry
1979
Corpus ID: 8540248
An enzyme which catalyzes the deamidation of thyroliberin (TRF; less than Glu-His-Pro-NH2) has been purified 110-fold from…
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Highly Cited
1976
Highly Cited
1976
One-step purification and properties of a two-peptide fatty acid synthetase from the uropygial gland of the goose.
J. Buckner
,
P. Kolattukudy
Biochemistry
1976
Corpus ID: 29656907
Cell-free extracts from the uropygial gland of goose catalyzed the incorporation of malonyl-CoA into normal fatty acids and…
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Highly Cited
1975
Highly Cited
1975
Factor-VIII-related antigen: multiple molecular forms in human plasma.
T. Zimmerman
,
J. Roberts
,
T. Edgington
Proceedings of the National Academy of Sciences…
1975
Corpus ID: 12697945
Analysis of Factor-VIII-related antigen (vWAg) in normal plasma by crossed immunoelectrophoresis reveals an asymmetric pattern…
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Highly Cited
1966
Highly Cited
1966
Measurement of the affinity and phosphorylation constants governing irreversible inhibition of cholinesterases by di-isopropyl phosphorofluoridate.
A. Main
,
F. Iverson
Biochemical Journal
1966
Corpus ID: 25881723
1. A procedure is described for determining the affinity constant K(a) and the phosphorylation constant k(p) for the inhibition…
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Highly Cited
1966
Highly Cited
1966
Dealkylation studies on inhibited acetylcholinesterase.
D. Coult
,
D. Marsh
,
G. Read
Biochemical Journal
1966
Corpus ID: 5244861
1. A rapid method for measuring the rate of dealkylation of organophosporus-inhibited enzymes is described. 2. The dealkylation…
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Highly Cited
1964
Highly Cited
1964
INHIBITION OF CHYMOTRYPSIN ACTIVITY IN CRYSTALLINE TRYPSIN PREPARATIONS.
V. Kostka
,
F. H. Carpenter
Journal of Biological Chemistry
1964
Corpus ID: 1136195
Investigations of protein structures have made extensive use of trypsin to obtain specific cleavage of the peptide chains at the…
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Highly Cited
1959
Highly Cited
1959
Intestinal absorption of insulin in the rat.
E. Danforth
,
R. O. Moore
Endocrinology
1959
Corpus ID: 34220653
The intestinal absorption of insulin in the rat has been investigated. Amorphous zinc-free insulin and proteolytic inhibitors…
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Highly Cited
1955
Highly Cited
1955
Cholinergic mechanism involved in function of mesodiencephalic activating system.
F. Rinaldi
,
H. Himwich
A M A Archives of Neurology & Psychiatry
1955
Corpus ID: 34621307
A previous investigation 1 dealt with the action of cholinergic drugs and of atropine on the electrical activity of the rabbit…
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Highly Cited
1949
Highly Cited
1949
The measurement of the cytochrome oxidase activity of enzyme preparations.
Pseudomonas Prunicola
Biochemical Journal
1949
Corpus ID: 12927903
containing 1 ml. 15 % glycerol solution, 1-0 ml. 0-1 M-sodium acetate, 0-5 ml. 0-3 M-bicarbonate solution and 0 5 ml. of the…
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