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Isocoumarins

Known as: 1-Isochromen-1-ones, 1H-2-Benzopyran-1-ones, Isocoumarins [Chemical/Ingredient] 
Compounds that differ from COUMARINS in having the positions of the ring and ketone oxygens reversed so the keto oxygen is at the 1-position of the… 
National Institutes of Health

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Narrower (41)

1-deoxyrubralactone4'-hydroxyasperentin4-acetylisocoumarin4-hydroxymellein
In Bloodagonistsantagonists & inhibitorsaspects of radiation effects

Papers overview

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Highly Cited
2015
Highly Cited
2015
Rh(III)-catalyzed C-H activation/cyclization of benzamides and diazo compounds to form isocoumarins and α-pyrones.
Rhodium-catalyzed intermolecular cyclization of benzamides and diazo compounds via C-H activation has been achieved to construct… 
Highly Cited
2012
Highly Cited
2012
Versatile synthesis of isocoumarins and α-pyrones by ruthenium-catalyzed oxidative C-H/O-H bond cleavages.
An inexpensive cationic ruthenium(II) catalyst enabled the expedient synthesis of isocoumarins through oxidative annulations of… 
2010
2010
Isolation of ugi four-component condensation primary adducts: a straightforward route to isocoumarins.
Ugi four-component condensation (Ugi-4CC) between 2-formylbenzoic acid, phenacylamine dimethyl acetal, and isocyanides afforded… 
2009
2009
Solid-phase synthesis of isocoumarins: a traceless halocyclization approach.
A straightforward and traceless solid-phase methodology was developed for the synthesis of isocoumarins. This two-step process… 
2004
2004
Alkylated Isocoumarins from Pituranthos Scoparius
Two isocoumarins have been isolated from the ethyl acetate extract of the root of Pituranthos scoparius: 3-n-propyl-5-methoxy-6… 
2004
2004
Mutagenicity of paepalantine dimer and glycoside derivatives from Paepalanthus bromelioides.
2002
2002
Construction of heterocyclic compounds by use of alpha-diazophosphonates: new one-pot syntheses of indoles and isocoumarins.
[reaction: see text] alpha-Diazophosphonates, which have extremely useful properties from a synthetic point of view, are… 
Highly Cited
2001
Highly Cited
2001
Anti-angiogenic activities of novel isocoumarins, AGI-7 and sescandelin.
strain by bioassay-guided fractionation and isolation. In this communication, we describe the isolation, identification, and anti… 
1994
1994
Mechanism-based isocoumarin inhibitors for blood coagulation serine proteases. Effect of the 7-substituent in 7-amino-4-chloro-3-(isothioureidoalkoxy)isocoumarins on inhibitory and anticoagulant…
A series of 7-amino-4-chloro-3-(3-isothioureidopropoxy)isocoumarin (NH2-CiTPrOIC) derivatives with various substituents at the 7… 
1992
1992
Substituted isocoumarins as inhibitors of complement serine proteases.
Inhibition of complement proteins D, B, C2, C1s, C1r, I, and the catalytic fragments Bb and C2a by substituted isocoumarins was… 
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