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Isoaspartic Acid

Known as: Isoaspartic Acid [Chemical/Ingredient], beta Aspartic Acid, beta-Aspartic Acid 
An ASPARTIC ACID residue in polypeptide chains that is linked at the beta-carboxyl group instead of at the normal, alpha-carboxyl group, polypeptide… 
National Institutes of Health

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Isoaspartate

Papers overview

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2007
2007
Localization of D-beta-aspartic acid-containing proteins in human eyes.
PURPOSE Biologically uncommon D-beta-aspartic acid (D-beta-Asp) has been detected in proteins from various human tissues in… 
Highly Cited
2001
Highly Cited
2001
Pronounced activity of enzymes through the incorporation into the core of polyion complex micelles made from charged block copolymers.
Highly Cited
2000
Highly Cited
2000
Differentiating alpha- and beta-aspartic acids by electrospray ionization and low-energy tandem mass spectrometry.
Spectra obtained by low-energy electrospray ionization tandem mass spectrometry (ESI-MS/MS) of 34 peptides containing aspartic… 
2000
2000
Development of improved high-performance liquid chromatography conditions for nonisotopic detection of isoaspartic acid to determine the extent of protein deamidation.
A rapid and accurate ion-pairing reversed-phase high-performance liquid chromatography (IP-RP-HPLC) procedure has been developed… 
2000
2000
Effect of lysine residues on the deamidation reaction of asparagine side chains.
The effect of lysine residues on the deamidation reaction of the asparagine side chain has been studied on the peptide and on its… 
1999
1999
Spontaneous deamidation and isomerization of Asn108 in prion peptide 106-126 and in full-length prion protein.
In prion-related encephalopathies, the cellular prion protein (PrP(C)) undergoes a change in conformation to become the scrapie… 
Highly Cited
1998
Highly Cited
1998
Selective deamidation of recombinant human stem cell factor during in vitro aging: isolation and characterization of the aspartyl and isoaspartyl homodimers and heterodimers.
During in vitro aging, deamidation of recombinant human stem cell factor produced in Escherichia. coli was detected by HPLC… 
Highly Cited
1996
Highly Cited
1996
Release of [3H]-d-Aspartate from Primary Astrocyte Cultures in Response to Raised External Potassium
There are significant Ca2+-independent increases in extracellular glutamate and aspartate during various CNS insults such as… 
1990
1990
Renin inhibitory peptides. A beta-aspartyl residue as a replacement for the histidyl residue at the P-2 site.
In an effort to decrease the size and to increase the hydrophilicity of the previously prepared renin inhibitory peptides, it was… 
Highly Cited
1986
Highly Cited
1986
Age-dependent accumulation of protein residues which can be hydrolyzed to D-aspartic acid in human erythrocytes.
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