Isatin

Known as: Isatin [Chemical/Ingredient], 2,3-Dioxoindoline, 2,3 Dioxoindoline 
An indole-dione that is obtained by oxidation of indigo blue. It is a MONOAMINE OXIDASE INHIBITOR and high levels have been found in urine of… (More)
National Institutes of Health

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35 relations

Narrower (28)

1-acetylisatin1-methylisatin 3-semicarbazone1-morpholinomethyl-5-methylisatin2,2'-pyridylisatogen
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In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

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2015
2015
Polarizable continuum model solvation analysis of some isatin derivatives
Polarizable continuum model analysis has been carried out for 5-chloroisatin, 5-methylisatin and 5-methoxyisatin in ten solvents… (More)
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Highly Cited
2007
Highly Cited
2007
Enterohemorrhagic Escherichia coli biofilms are inhibited by 7-hydroxyindole and stimulated by isatin.
Since indole is present at up to 500 microM in the stationary phase and is an interspecies biofilm signal (J. Lee, A. Jayaraman… (More)
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2007
2007
In vitro cytotoxicity evaluation of some substituted isatin derivatives.
A range of substituted 1H-indole-2,3-diones (isatins) were synthesized using standard procedures and their cytotoxicity evaluated… (More)
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2007
2007
Biological targets for isatin and its analogues: Implications for therapy
Isatin and its metabolites are constituents of many natural substances. They are also components of many synthetic compounds… (More)
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Highly Cited
2007
Highly Cited
2007
Synthesis, antibacterial, antifungal and antiviral activity evaluation of some new bis-Schiff bases of isatin and their derivatives.
Twelve new bis-Schiff bases of isatin, benzylisatin and 5-fluoroisatin 3a-3l were prepared by condensation of isatin… (More)
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Highly Cited
2005
Highly Cited
2005
Biological activities of isatin and its derivatives.
Isatin is an endogenous compound identified in humans that possesses a wide range of biological activities. Isatin has anxiogenic… (More)
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2004
2004
Anticonvulsant activity of Schiff bases of isatin derivatives.
Schiff bases of N-methyl and N-acetyl isatin derivatives with different aryl amines have been synthesized and screened for… (More)
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1999
1999
Synthesis, antibacterial, antifungal and anti-HIV evaluation of Schiff and Mannich bases of isatin derivatives with 3-amino-2-methylmercapto quinazolin-4(3H)-one.
Isatin (Indole 2,3-dione), its 5-chloro and 5-bromo derivatives were added to 3-amino-2-methylmercapto quinazolin-4(3H)-one to… (More)
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1988
1988
Isatin: identity with the purified endogenous monoamine oxidase inhibitor tribulin.
Purified tribulin, an endogenous monoamine oxidase (MAO) inhibitor, has been identified by direct probe insertion mass… (More)
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Highly Cited
1950
Highly Cited
1950
The determination of hydroxyproline.
There has been a great need for a satisfactory method for the determination of hydroxyproline to facilitate the study of the… (More)
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