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Iron Overload

Known as: Overload, Iron, iron overloading, excesses iron 
A condition in which the body takes up and stores more iron than it needs. The extra iron is stored in the liver, heart, and pancreas, which may… 
National Institutes of Health

Related topics

Related topics

10 relations
DeferoxamineIn BloodMicrobiologicalchemically induced

Narrower (1)

Hemosiderosis

Broader (1)

Iron Metabolism Disorders

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2008
Review
2008
Regulation of iron acquisition and storage: consequences for iron-linked disorders
Mammalian iron homeostasis must be meticulously regulated so that this essential element is available for use, but at the same… 
Highly Cited
2007
Highly Cited
2007
Identification of IRS-1 Ser-1101 as a target of S6K1 in nutrient- and obesity-induced insulin resistance
S6K1 has emerged as a critical signaling component in the development of insulin resistance through phosphorylation and… 
Highly Cited
2006
Highly Cited
2006
Oxidative stress and inflammation in iron‐overloaded patients with β‐thalassaemia or sickle cell disease
Blood transfusion therapy is life‐saving for patients with β‐thalassaemia and sickle cell disease (SCD), but often results in… 
Highly Cited
2005
Highly Cited
2005
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload.
Iron homeostasis plays a critical role in many physiological processes, notably synthesis of heme proteins. Dietary iron sensing… 
Review
2004
Review
2004
The effect of alcohol consumption on the prevalence of iron overload, iron deficiency, and iron deficiency anemia.
BACKGROUND & AIMS Our aim was to investigate the relationship between alcohol consumption and iron overload, iron deficiency, or… 
Highly Cited
2003
Highly Cited
2003
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
Review
2001
Review
2001
Chemistry and biology of eukaryotic iron metabolism.
Review
2000
Review
2000
Iron metabolism: iron deficiency and iron overload.
  • N. Andrews
  • Annual review of genomics and human genetics…
  • 2000
  • Corpus ID: 41892108
Iron is an essential cofactor in a variety of cellular processes. Except for a few unusual bacterial species, iron is… 
Highly Cited
1983
Highly Cited
1983
Hepatic lipid peroxidation in vivo in rats with chronic iron overload.
Peroxidative decomposition of cellular membrane lipids is a postulated mechanism of hepatocellular injury in parenchymal iron… 
Highly Cited
1974
Highly Cited
1974
Ferritin in serum: diagnosis of iron deficiency and iron overload in infants and children.
Ferritin in serum was quantitated by radioimmunoassay to determine the usefulness of this assay in reflecting iron stores during… 
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