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Iron Overload

Known as: Overload, Iron, iron overloading, excesses iron 
A condition in which the body takes up and stores more iron than it needs. The extra iron is stored in the liver, heart, and pancreas, which may… 
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Expression of hepcidin, a key regulator of intestinal iron absorption, can be induced in vitro by several bone morphogenetic… 
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Highly Cited
2005
Highly Cited
2005
BACKGROUND Iron overload and hemochromatosis are common, treatable conditions. HFE genotypes, levels of serum ferritin… 
Review
2005
Review
2005
The evolution of iron chelators from a range of primordial siderophores and aromatic heterocyclic ligands has lead to the… 
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Highly Cited
2004
Highly Cited
2004
Juvenile hemochromatosis is an early-onset autosomal recessive disorder of iron overload resulting in cardiomyopathy, diabetes… 
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Highly Cited
2004
Highly Cited
2004
Hepcidin is a peptide hormone secreted by the liver in response to iron loading and inflammation. Decreased hepcidin leads to… 
Highly Cited
2001
Highly Cited
2001
Considering that the development of hepatic lesions related to iron overload diseases might be a result of abnormally expressed… 
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Highly Cited
2001
Highly Cited
2001
AIMS To develop and validate a non-invasive method for measuring myocardial iron in order to allow diagnosis and treatment before… 
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Highly Cited
2001
Highly Cited
2001
We previously reported the disruption of the murine gene encoding the transcription factor USF2 and its consequences on glucose… 
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Highly Cited
2000
Highly Cited
2000
Iron absorption by the duodenal mucosa is initiated by uptake of ferrous Fe(II) iron across the brush border membrane and… 
Highly Cited
1994
Highly Cited
1994
BACKGROUND To determine whether deferoxamine prevents the complications of transfusional iron overload in thalassemia major, we…