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Deferoxamine

Known as: Butanediamide, N'-(5-((4-((5-(acetylhydroxyamino)pentyl)amino)-1,4-dioxobutyl)hydroxyamino)pentyl)-N-(5-aminopentyl)-N-hydroxy-, DFOM, Deferoximine 
An iron-chelating agent that binds free iron in a stable complex, preventing it from engaging in chemical reactions. Deferoxamine chelates iron from… 
National Institutes of Health

Related topics

Related topics

36 relations

Narrower (13)

4-isothiocyanatobenzyl-desferrioxamine40SD02DesferalN-methylanthranilic-desferrioxamine
AnuriaBone DiseasesChelation TherapyCorneal Diseases

Broader (4)

Chelating AgentsSiderophoresferoxaminehydroxamate

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2005
Highly Cited
2005
Siderophore-manganese(III) interactions. I. Air-oxidation of manganese(ll) promoted by desferrioxamine B.
Recent studies suggest that aqueous Mn(ll) complexes, particularly those with non-carboxylated ligands such as microbial… 
Highly Cited
2004
Highly Cited
2004
Synthesis and characterization of diperfluorooctyl-substituted phenylene-thiophene oligomers as n-type semiconductors. Molecular structure-film microstructure-mobility relationships, organic field…
A new series of mixed phenylene−thiophene oligomers with terminal n-perfluorooctyl groups has been synthesized. These compounds… 
Highly Cited
1988
Highly Cited
1988
Spin trapping of free radical species produced during the microsomal metabolism of ethanol.
Highly Cited
1988
Highly Cited
1988
Toxic consequence of the abrupt depletion of glutathione in cultured rat hepatocytes.
Highly Cited
1985
Highly Cited
1985
Asbestos-catalysed lipid peroxidation and its inhibition by desferroxamine.
In an effort to understand the properties of asbestos fibres that might contribute to their being toxic, we incubated three… 
Review
1985
Review
1985
Role of iron ions in the genesis of reperfusion injury following successful cardiopulmonary resuscitation: preliminary data and a biochemical hypothesis.
Highly Cited
1984
Highly Cited
1984
Superoxide generation by NADPH-cytochrome P-450 reductase: the effect of iron chelators and the role of superoxide in microsomal lipid peroxidation.
Highly Cited
1981
Highly Cited
1981
Role of iron and ethylenediaminetetraacetic acid in the bactericidal activity of a superoxide anion-generating system.
Highly Cited
1978
Highly Cited
1978
Iron uptake by Chang cells from transferrin, nitriloacetate and citrate complexes: the effects of iron-loading and chelation with desferrioxamine.
Highly Cited
1974
Highly Cited
1974
LONG‐TERM DESFERRIOXAMINE THERAPY IN THALASSEMIA
At University College Hospital and the Whittington Hospital in London we have 31 children with thalassemia major, most of them… 
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