Ipratropium

Known as: (3-endo,8-syn)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo(3.2.1)octane, N-Isopropylatropine, (endo,syn)-(+-)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo(3.2.1)octane 
A synthetic derivative of the alkaloid atropine with anticholinergic properties. Ipratropium antagonizes the actions of acetylcholine at… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
The degree of acute improvement in spirometric indices after bronchodilator inhalation varies among chronic obstructive pulmonary… (More)
  • table 1
  • figure 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
Highly Cited
2004
Highly Cited
2004
BACKGROUND The issue of whether regular use of an inhaled beta2-adrenergic agonist worsens airflow and clinical outcomes in… (More)
Is this relevant?
Highly Cited
2003
Highly Cited
2003
BACKGROUND A limited or absent bronchodilator response is used to classify chronic obstructive pulmonary disease (COPD) and can… (More)
  • table 1
  • figure 1
  • figure 2
  • figure 4
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Tiotropium, a novel once-daily inhaled anticholinergic, has been shown to improve lung function over a 24-h period. In order to… (More)
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2002
Highly Cited
2002
This report deals with deaths and hospitalizations during the 5-year Lung Health Study, as documented by examination of… (More)
Is this relevant?
Highly Cited
2001
Highly Cited
2001
We compared the effectiveness of inhaled formoterol with that of ipratropium in the treatment of chronic obstructive pulmonary… (More)
Is this relevant?
Highly Cited
1999
Highly Cited
1999
STUDY OBJECTIVES To examine and compare the efficacy and safety of salmeterol xinafoate, a long-acting inhaled beta2-adrenergic… (More)
  • table 2
  • table 1
  • table 3
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1999
Highly Cited
1999
STUDY OBJECTIVE To conduct a post hoc pharmacoeconomic evaluation of two double-blind, randomized, prospective, parallel group… (More)
Is this relevant?
Highly Cited
1998
Highly Cited
1998
BACKGROUND Patients can have several illnesses concurrently, yet some of these diseases may be neglected if one problem consumes… (More)
Is this relevant?
1981
1981
Ipratropium bromide was given to patients admitted to hospital with acute asthma. A cumulative-dose-response technique in six… (More)
  • figure 2
  • figure 1
Is this relevant?