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Chronic obstructive pulmonary disease.
1 Chronic Obstructive Pulmonary Disease Chronic obstructive pulmonary disease (COPD) is a major public health problem, a cause of poor health and death worldwide and a significant contributor to… Expand
Genetic studies of body mass index yield new insights for obesity biology
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass… Expand
Development, validity and responsiveness of the Clinical COPD Questionnaire
- T. van der Molen, B. Willemse, S. Schokker, N. T. ten Hacken, D. Postma, E. Juniper
- Health and quality of life outcomes
- 28 April 2003
BackgroundThe new Global Obstructive Lung Disease (GOLD) guidelines advice to focus treatment in Chronic Obstructive Pulmonary Disease (COPD) on improvement of functional state, prevention of disease… Expand
An official American Thoracic Society public policy statement: Novel risk factors and the global burden of chronic obstructive pulmonary disease.
- M. Eisner, N. Anthonisen, +6 authors J. Balmes
- American journal of respiratory and critical care…
- 1 September 2010
RATIONALE Although cigarette smoking is the most important cause of chronic obstructive pulmonary disease (COPD), a substantial proportion of COPD cases cannot be explained by smoking alone. … Expand
Optimal assessment and management of chronic obstructive pulmonary disease (COPD). The European Respiratory Society Task Force.
Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality. In the European Union, COPD and asthma, together with pneumonia, are the third most common cause of death. In… Expand
Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group.
- R. Pauwels, C. Löfdahl, +4 authors A. Ullman
- The New England journal of medicine
- 13 November 1997
BACKGROUND The role of long-acting, inhaled beta2-agonists in treating asthma is uncertain. In a double-blind study, we evaluated the effects of adding inhaled formoterol to both lower and higher… Expand
Protein tyrosine nitration: selectivity, physicochemical and biological consequences, denitration, and proteomics methods for the identification of tyrosine-nitrated proteins.
- N. Abello, H. Kerstjens, D. Postma, R. Bischoff
- Chemistry, Medicine
- Journal of proteome research
- 1 June 2009
Protein tyrosine nitration (PTN) is a post-translational modification occurring under the action of a nitrating agent. Tyrosine is modified in the 3-position of the phenolic ring through the addition… Expand
The Asthma-COPD Overlap Syndrome.
Although in textbooks asthma and chronic obstructive pulmonary disease (COPD) are viewed as distinct disorders, there is increasing awareness that many patients have features of both. This article… Expand
Ambient air pollution and low birthweight: a European cohort study (ESCAPE).
- M. Pedersen, L. Giorgis-Allemand, +49 authors R. Slama
- The Lancet. Respiratory medicine
- 1 November 2013
BACKGROUND Ambient air pollution has been associated with restricted fetal growth, which is linked with adverse respiratory health in childhood. We assessed the effect of maternal exposure to low… Expand
Air pollution and development of asthma, allergy and infections in a birth cohort
Few studies have addressed associations between traffic-related air pollution and respiratory disease in young children. The present authors assessed the development of asthmatic/allergic symptoms… Expand