Interleukin-3 Receptor alpha Subunit

Known as: Interleukin-3 Receptor alpha Chain, Antigen, CD123, CD123 
A low affinity interleukin-3 receptor subunit that combines with the CYTOKINE RECEPTOR COMMON BETA SUBUNIT to form a high affinity receptor for… (More)
National Institutes of Health

Papers overview

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Highly Cited
2016
Highly Cited
2016
Potent CD19-directed immunotherapies, such as chimeric antigen receptor T cells (CART) and blinatumomab, have drastically changed… (More)
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Highly Cited
2014
Highly Cited
2014
As significant numbers of acute myeloid leukemia (AML) patients are still refractory to conventional therapies or experience… (More)
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Review
2011
Review
2011
Accumulating evidence indicates that many human cancers are organized as a cellular hierarchy initiated and maintained by self… (More)
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2006
2006
Plasmacytoid dendritic cells (PDC) are the natural type I IFN-producing cells that produce large amounts of IFN-alpha in response… (More)
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2005
2005
Leukemic blasts from patients with acute myeloid leukemia (AML) frequently express high levels of the interleukin-3 receptor… (More)
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2004
2004
In a previous study we have shown that the interleukin-3 receptor alpha chain (IL-3Ralpha) is over expressed in about 45% of… (More)
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Highly Cited
2002
Highly Cited
2002
Dendritic cells (DCs) are key antigen-presenting cells for stimulating immune responses and they are now being investigated in… (More)
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Highly Cited
2001
Highly Cited
2001
BACKGROUND AND OBJECTIVES The hematopoietic system is controlled by growth factors (cytokines) which can influence cell survival… (More)
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Highly Cited
2000
Highly Cited
2000
Recent studies suggest that the population of malignant cells found in human acute myelogenous leukemia (AML) arises from a rare… (More)
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1995
1995
The interleukin-3 receptor (IL-3R) is composed of alpha and beta subunits, members of the class I cytokine receptor family. Here… (More)
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