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Interleukin-27

Known as: IL-17D, Interleukin 27, Interleukin-27 [Chemical/Ingredient] 
A heterodimeric cytokine composed of the IL-27p28 and EBI3 subunits. It is produced primarily by antigen-presenting cells after stimulation by… 
National Institutes of Health

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IL17D geneIL27 geneIn BloodProcess of secretion

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IL27 protein, human

Papers overview

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2016
2016
IL-27 Is Essential for Suppression of Experimental Allergic Asthma by the TLR7/8 Agonist R848 (Resiquimod)
Different models of experimental allergic asthma have shown that the TLR7/8 agonist resiquimod (R848) is a potential inhibitor of… 
Highly Cited
2014
Highly Cited
2014
A possible role for interleukin 37 in the pathogenesis of Behcet's disease.
Interleukin 37 has been found to play a significant regulatory role in the innate immune response. It is not yet known whether IL… 
2014
2014
Combination Treatment with Apricoxib and IL-27 Enhances Inhibition of Epithelial-Mesenchymal Transition in Human Lung Cancer Cells through a STAT1 Dominant Pathway.
BACKGROUND The cyclooxygenase 2 (COX-2) pathway has been implicated in the molecular pathogenesis of many malignancies, including… 
2012
2012
IL-27 Regulates IL-18 Binding Protein in Skin Resident Cells
IL-18 is an important mediator involved in chronic inflammatory conditions such as cutaneous lupus erythematosus, psoriasis and… 
2012
2012
Regulation of Proinflammatory Th17 Responses during Trypanosoma cruzi Infection by IL-12 Family Cytokines
Previously, we reported that the transcription factor T-bet (Tbx21) regulates Th17 responses to Trypanosoma cruzi infection in an… 
Highly Cited
2010
Highly Cited
2010
Impact of HIV infection, highly active antiretroviral therapy, and hepatitis C coinfection on serum interleukin-27
A newly described cytokine, interleukin-27 (IL-27), that activates naive CD4 T cells, has recently been shown to be an anti-HIV… 
2010
2010
Changes of cytokines and IgG antibody in chickens vaccinated with DNA vaccines encoding Eimeria acervulina lactate dehydrogenase.
Review
2009
Review
2009
Role of interleukin-17F in asthma.
A new family of cytokines, the interleukin (IL)-17 family, has recently been defined, which reveals unique functions and distinct… 
2009
2009
Association of variants in the interleukin‐27 and interleukin‐12 gene with nasopharyngeal carcinoma
Nasopharyngeal carcinoma (NPC) is multifactorial, and the genetic background may be a crucial etiologic factor. Interleukin‐12… 
2008
2008
Amelioration of delayed-type hypersensitivity responses by IL-27 administration.
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