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IL27 protein, human

Known as: Interleukin-27, human, IL-27 protein, human, Interleukin 27 
A heterodimeric cytokine that is comprised of interleukin-27 subunits alpha and beta. This protein complex is involved in the regulation of B- and T… 
National Institutes of Health

Related topics

Related topics

8 relations
IL17D geneIL27 geneImmune responseinflammatory response

Broader (2)

Interleukin-27Interleukins

Narrower (1)

Interleukin-27 Subunit Alpha, human

Papers overview

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2017
2017
Increased levels of interleukin 27 in patients with early clinical stages of non-small cell lung cancer.
INTRODUCTION    Interleukin 27 (IL‑27) is a cytokine secreted mostly by antigen‑presenting cells. It is important for the immune… 
2017
2017
The cross talk between cervical carcinoma cells and vascular endothelial cells mediated by IL‐27 restrains angiogenesis
To explore whether cervical carcinoma cell‐derived interleukin‐27 (IL‐27) modulates the angiogenesis of vascular endothelial… 
2017
2017
The role of interleukin‐27 in predicting spontaneous HBeAg seroconversion in chronic hepatitis B infection
Hepatitis B e seroconversion, associated with preceding hepatic inflammation, marks the transition from immune active to residual… 
2016
2016
Mutant p53 in concert with an interleukin‐27 receptor alpha deficiency causes spontaneous liver inflammation, fibrosis, and steatosis in mice
The cellular and molecular etiology of unresolved chronic liver inflammation remains obscure. Whereas mutant p53 has gain‐of… 
2016
2016
Association of the Interleukin-27 Gene Expression and Hepatitis B Virus Infection in Liver Transplanted Patients.
OBJECTIVES Hepatitis B viral infection is among the most common causes of cirrhosis and hepatocellular carcinoma and a frequent… 
2015
2015
Therapeutic potential of interleukin-27 against cancers in preclinical mouse models
Since we first reported the antitumor efficacy of IL-27 in 2004, accumulating evidence obtained by several groups using a variety… 
2011
2011
T cell‐specific overexpression of interleukin‐27 receptor α subunit (WSX‐1) prevents spontaneous skin inflammation in MRL/lpr mice
Background  Interleukin (IL)‐27 and WSX‐1, the receptor α‐specific subunit, have been shown to play important roles in initiating… 
2011
2011
Mutations in the transmembrane and juxtamembrane domains enhance IL27R transforming activity.
Cytokines and their receptors regulate haemopoiesis by controlling cellular growth, survival and differentiation. Thus it is not… 
2011
2011
Circulating interleukin‐27 levels in Helicobacter pylori‐infected patients with gastric or duodenal ulcers, independent of the bacterial cytotoxin‐associated gene A virulence factor
OBJECTIVE:  The aim was to evaluate the interleukin (IL)‐27 levels in Helicobacter pylori (H. pylori)‐infected patients with… 
2007
2007
Disruption of Interleukin-27 Signaling Results in Impaired Gamma Interferon Production but Does Not Significantly Affect Immunopathology in Murine Schistosome Infection
ABSTRACT In schistosomiasis mansoni, parasite eggs cause hepatointestinal granulomatous inflammation and fibrosis mediated by CD4… 
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