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Interleukin-15
Known as:
MGC9721
, IL-15
, IL15
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Interleukin-15 (162 aa, ~18 kDa) is encoded by the human IL15 gene. This protein plays a role in the regulation of both proliferation and activation…
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National Institutes of Health
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Related topics
Related topics
26 relations
Cell Proliferation Regulatory Process
Cytokine Gene
Cytokine Network Pathway
Cytokine Receptor Binding
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Narrower (2)
IL-15-Fcgamma2a protein, human
Recombinant Interleukin-15
Broader (2)
Interleukins
Lymphokines
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Myxoma Virus Expressing a Fusion Protein of Interleukin-15 (IL15) and IL15 Receptor Alpha Has Enhanced Antitumor Activity
Vesna Tosic
,
Diana L. Thomas
,
+5 authors
E. Roy
PLoS ONE
2014
Corpus ID: 1528704
Myxoma virus, a rabbit poxvirus, can efficiently infect various types of mouse and human cancer cells. It is a strict rabbit…
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2012
2012
The use of an in vitro 3D melanoma model to predict in vivo plasmid transfection using electroporation.
B. Marrero
,
R. Heller
Biomaterials
2012
Corpus ID: 39136892
2009
2009
High concentrations of interleukin 15 in breast milk are associated with protection against postnatal HIV transmission.
J. Walter
,
M. Ghosh
,
+5 authors
G. Aldrovandi
Journal of Infectious Diseases
2009
Corpus ID: 32739462
Given the central role that interleukin 15 (IL-15) plays in human immunodeficiency virus (HIV) immunity, we hypothesized that IL…
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2008
2008
Interleukin-15 and NK1.1+ Cells Provide Innate Protection against Acute Salmonella enterica Serovar Typhimurium Infection in the Gut and in Systemic Tissues
A. Ashkar
,
S. Reid
,
E. Verdú
,
Kun Zhang
,
B. Coombes
Infection and Immunity
2008
Corpus ID: 17406897
ABSTRACT Control of bacterial colonization at mucosal surfaces depends on rapid activation of the innate immune system…
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Highly Cited
2006
Highly Cited
2006
Peripheral blood T lymphocytes from patients with early rheumatoid arthritis express RANKL and interleukin-15 on the cell surface and promote osteoclastogenesis in autologous monocytes.
M. Miranda-Carús
,
M. Benito-Miguel
,
+4 authors
E. Martı́n-Mola
Arthritis & Rheumatism
2006
Corpus ID: 20978969
OBJECTIVE To investigate the osteoclastogenic potential of T cells from the peripheral blood (PB) and synovial fluid (SF) of…
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Highly Cited
2006
Highly Cited
2006
Family based association analysis of the IL2 and IL15 genes in allergic disorders
Ulla Christensen
,
A. Haagerup
,
H. Binderup
,
J. Vestbo
,
T. Kruse
,
A. Børglum
European Journal of Human Genetics
2006
Corpus ID: 20592064
Allergic diseases affect an increasing number of individuals and are a major global health problem. A substantial genetic…
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2000
2000
In vitro release of interleukin-15 by broncho-alveolar lavage cells and peripheral blood mononuclear cells from patients with different lung diseases.
G. Zissel
,
I. Bäumer
,
Max Schlaak
,
J. Müller-Quernheim
European Cytokine Network
2000
Corpus ID: 43006807
IL-15 shares several biological activities with IL-2 and uses the b and g chain of the IL-2 receptor. In addition to its T-cell…
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2000
2000
Restoration of cytotoxic T lymphocyte function in malignant pleural effusion: interleukin-15 vs. interleukin-2.
Y. Chen
,
C. Ting
,
+4 authors
R. Perng
Journal of Interferon and Cytokine Research
2000
Corpus ID: 29374695
The present study attempts to define the role of interleukin-15 (IL-15), as compared with IL-2, in generating cytotoxic T…
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1999
1999
The generation of human dendritic and NK cells from hemopoietic progenitors induced by interleukin‐15
S. Bykovskaia
,
M. Buffo
,
+8 authors
J. Shogan
Journal of Leukocyte Biology
1999
Corpus ID: 6975518
Interleukin‐15 (IL‐15) is a pleiotropic cytokine that induces the generation and differentiation of lymphoid cells and shares…
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Highly Cited
1998
Highly Cited
1998
Interleukin-15 May Be Responsible for Early Activation of Intestinal Intraepithelial Lymphocytes after Oral Infection with Listeria monocytogenes in Rats
K. Hirose
,
Hirohiko Suzuki
,
+4 authors
Y. Yoshikai
Infection and Immunity
1998
Corpus ID: 28364649
ABSTRACT Exogenous interleukin-15 (IL-15) stimulates intestinal intraepithelial lymphocytes (i-IEL) from mice to proliferate and…
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