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Recombinant Interleukin-15

Known as: rIL15, rhIL-15, IL15 
A recombinant agent that is chemically identical or similar to the endogenous form of the human cytokine interleukin-15 (IL-15) with immunomodulating… 
National Institutes of Health

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IL15 geneInhibition of Cell Proliferation

Broader (1)

Interleukin-15

Papers overview

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2018
2018
In Vitro Xenoantigen Stimulated Human Tr1 Cells Enhanced Suppression of the Xenogeneic T Cell Response with Upregulated Expression of CD39
Introduction Life-long immunosuppression is required to prevent xenograft rejection. Induction of antigen specific tolerance by… 
2015
2015
CITN11-02 interim trial results: subcutaneous administration of recombinant human IL-15 (rhIL-15) is associated with expansion of peripheral blood CD56+ NK cells and CD8+ T cells
Meeting abstracts The Cancer Immunotherapy Trials Network is conducting a Phase I, dose-escalation study of subcutaneous (SQ… 
2013
2013
IL-15 Primes a Highly Potent Anti-Leukemia Response By CD56bright NK Cells
Background NK cells are innate lymphocytes that are important for host defense against infections, and are potent anti-cancer… 
Review
2010
Review
2010
Novel Gamma-Chain Cytokines as Candidate Immune Modulators in Immune Therapies for Cancer
Cytokines that signal through the common-gamma chain are potent growth factors for T cells and natural killer cells. Interleukin… 
2009
2009
Design and analysis of a compact EUV interferometric lithography system
A small-scale interferometric EUV exposure system is pre- sented, based on Talbot interferometric imaging. In this approach… 
2008
2008
Role of the p38 MAPK pathway in induction of iNOS expression in human leukocytes.
Inducible nitric oxide synthase (iNOS) is one of the enzymes responsible for NO production in neutrophils (PMN) and in peripheral… 
2005
2005
[Effect of rhIL-15 on TLR2 expression and apoptosis of PMN from patients with Lyme disease].
In this study we estimated the expression of TLR2 and apoptosis of PMN in patients with Lyme disease. The cells were isolated… 
2003
2003
Expansion of EBV latent membrane protein 2a specific cytotoxic T cells for the adoptive immunotherapy of EBV latency type 2 malignancies: influence of recombinant IL12 and IL15.
BACKGROUND EBV-associated malignancies with a Type II latency gene expression pattern, such as EBV-positive HD, or nasopharyngeal… 
2003
2003
Patients on Chronic Hemodialysis Have No Intrinsic Lymphocyte Defect upon Stimulation with Interleukin-2, Interleukin-15 or Tumor Necrosis Factor-Alpha
Background: Patients on chronic hemodialysis (HD) suffer from general immune incompetence, resulting in a high incidence of… 
2000
2000
Functional responses of T cells blocked by anti-CD25 antibody therapy during cardiac rejection.
BACKGROUND Despite anti-CD25 (interleukin [IL]-2 receptor alpha chain) monoclonal antibody (mAb) therapy, rejection can still… 
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