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Recombinant Interleukin-15

Known as: rIL15, rhIL-15, IL15 
A recombinant agent that is chemically identical or similar to the endogenous form of the human cytokine interleukin-15 (IL-15) with immunomodulating… Expand
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
PURPOSE Interleukin-15 (IL-15) has significant potential in cancer immunotherapy as an activator of antitumor CD8 T and natural… Expand
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2013
2013
Recombinant human IL-15 (rhIL-15) is one of the most promising cytokines for antitumor immunotherapy. In physiology IL-15 trans… Expand
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2012
2012
Introduction The purpose of this study was to examine the role of RA Synovial Fibroblast (RASFib) IL-15 expression on B cell… Expand
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Highly Cited
2011
Highly Cited
2011
IL-15 uses the heterotrimeric receptor IL-2/IL-15Rβ and the γ chain shared with IL-2 and the cytokine-specific IL-15Rα. Although… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Many renal cancer patients experience disease recurrence after immunotherapy or combined treatments due to persistence… Expand
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2007
2007
AimSeveral lines of evidence suggest that NK cell immunotherapy may represent a successful approach in neuroblastoma (NB… Expand
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Highly Cited
2005
Highly Cited
2005
Current models of T cell memory implicate a critical role for IL-7 in the effector-to-memory transition, raising the possibility… Expand
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2003
2003
Interleukin 15 (IL-15) is a potent stimulator of proliferation and an inhibitor of apoptosis in lymphocytes. We attempted to… Expand
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Highly Cited
2000
Highly Cited
2000
Cytokines are important in the regulation of haematopoiesis and immune responses, and can influence lymphocyte development. Here… Expand
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Highly Cited
2000
Highly Cited
2000
In eukaryotic cells, protein disulfide isomerase (PDI) found in the endoplasmic reticulum (ER) catalyzes disulfide bond exchange… Expand
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