Skip to search formSkip to main contentSkip to account menu

Recombinant Interleukin-15

Known as: rIL15, rhIL-15, IL15 
A recombinant agent that is chemically identical or similar to the endogenous form of the human cytokine interleukin-15 (IL-15) with immunomodulating… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
PURPOSE Interleukin-15 (IL-15) has significant potential in cancer immunotherapy as an activator of antitumor CD8 T and natural… 
Highly Cited
2015
Highly Cited
2015
IL15 stimulates T-cell and NK-cell responses, but not Tregs. The antitumor efficacy, biodistribution, and toxicity of an IL15… 
Review
2015
Review
2015
Preclinical models revealed that the immune system can mediate rejection of established tumors, but direct evidence in humans has… 
Review
2014
Review
2014
Natural killer (NK) cells are innate lymphoid cells important for host defense against pathogens and mediate antitumor immunity… 
Review
2014
Review
2014
In obesity, chronic inflammation is believed to induce insulin resistance and impairs adipose tissue function. Although this view… 
Highly Cited
2011
Highly Cited
2011
IL-15 uses the heterotrimeric receptor IL-2/IL-15Rβ and the γ chain shared with IL-2 and the cytokine-specific IL-15Rα. Although… 
Highly Cited
2005
Highly Cited
2005
Current models of T cell memory implicate a critical role for IL-7 in the effector-to-memory transition, raising the possibility… 
Highly Cited
2000
Highly Cited
2000
Cytokines are important in the regulation of haematopoiesis and immune responses, and can influence lymphocyte development. Here… 
Highly Cited
2000
Highly Cited
2000
In eukaryotic cells, protein disulfide isomerase (PDI) found in the endoplasmic reticulum (ER) catalyzes disulfide bond exchange…