Recombinant Interleukin-15

Known as: rIL15, rhIL-15, IL15 
A recombinant agent that is chemically identical or similar to the endogenous form of the human cytokine interleukin-15 (IL-15) with immunomodulating… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1994-2018
024619942018

Papers overview

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Highly Cited
2015
Highly Cited
2015
PURPOSE Interleukin-15 (IL-15) has significant potential in cancer immunotherapy as an activator of antitumor CD8 T and natural… (More)
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2011
2011
IL-15 uses the heterotrimeric receptor IL-2/IL-15Rβ and the γ chain shared with IL-2 and the cytokine-specific IL-15Rα. Although… (More)
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2011
2011
BACKGROUND Many renal cancer patients experience disease recurrence after immunotherapy or combined treatments due to persistence… (More)
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2011
2011
Natural Killer cells can distinguish between healthy and malignant cells and have the unique ability to lyse tumour cells without… (More)
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2010
2010
Mammalian interferon regulatory factor (IRF)4 (PIP, LSIRF, and ICSAT) and IRF8 (ICSBP) are known to be critical in regulating a… (More)
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2008
2008
Transplantable experimental tumor models were constructed to study the activities of recombinant human interleukin-15 (rhIL-15… (More)
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2007
2007
Several lines of evidence suggest that NK cell immunotherapy may represent a successful approach in neuroblastoma (NB) patients… (More)
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2006
2006
Human nonobese diabetic-severe combined immune deficiency (NOD-SCID) mouse chimeras have been widely used as an in vivo model to… (More)
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Highly Cited
2005
Highly Cited
2005
Current models of T cell memory implicate a critical role for IL-7 in the effector-to-memory transition, raising the possibility… (More)
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2000
2000
In eukaryotic cells, protein disulfide isomerase (PDI) found in the endoplasmic reticulum (ER) catalyzes disulfide bond exchange… (More)
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