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Interleukin-13

Known as: Interleukin-13 [Chemical/Ingredient], IL 13, Interleukin 13 
One of a group of related proteins made by leukocytes (white blood cells) and other cells in the body. IL-13 is made by a type of T lymphocyte. It… 
National Institutes of Health

Related topics

Related topics

29 relations
AsthmaCell Proliferation Regulatory ProcessCytokine GeneCytokine Network Pathway

Narrower (4)

IL13-PE38IL13-PE38QQRRecombinant Interleukin-13hIL-13-PE38QQR

Broader (1)

cytokine

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2011
Highly Cited
2011
Asthma phenotypes and interleukin-13--moving closer to personalized medicine.
Asthma is a chronic inflammatory disease of the airways manifested by reversible airflow obstruction and airway… 
Highly Cited
2006
Highly Cited
2006
IL-17A promotes the growth of airway epithelial cells through ERK-dependent signaling pathway.
Highly Cited
2005
Highly Cited
2005
Therapeutic Dosing with Anti-Interleukin-13 Monoclonal Antibody Inhibits Asthma Progression in Mice
In vivo models have demonstrated that interleukin-13 (IL-13) plays an important role in asthma; however, few studies have… 
Highly Cited
2001
Highly Cited
2001
Regulation of IL-13 production by histamine in cloned murine T helper type 2 cells.
Highly Cited
2000
Highly Cited
2000
Interleukin-13 fusion cytotoxin as a potent targeted agent for AIDS-Kaposi's sarcoma xenograft.
Clinically advanced and rapidly progressive AIDS-associated Kaposi sarcoma (AIDS-KS) tumors require an aggressive tumor-directed… 
Highly Cited
1996
Highly Cited
1996
T helper 2 cytokines differently regulate monocyte chemoattractant protein-1 production by human peripheral blood monocytes and alveolar macrophages.
Th2 cytokines, such as IL-4, IL-10, and IL-13, suppress proinflammatory cytokine production by monocytes/macrophages. Since… 
Highly Cited
1996
Highly Cited
1996
Immunoregulatory properties of IL‐13 in patients with inflammatory bowel disease; comparison with IL‐4 and IL‐10
Activated monocytes with increased expression of proinflammatory cytokines play a major role in inflammatory bowel disease (IBD… 
Highly Cited
1996
Highly Cited
1996
Human IL-13 production is negatively influenced by CD3 engagement. Enhancement of IL-13 production by cyclosporin A.
IL-13, a T cell-derived cytokine, shares many of its biologic activities with the Th2 cytokine IL-4, including induction of a… 
Highly Cited
1996
Highly Cited
1996
Coexpression of the interleukin-13 and interleukin-4 genes correlates with their physical linkage in the cytokine gene cluster on human chromosome 5q23-31.
Interleukin-13 (IL-13) and IL-4 are cytokines produced by T cells that are encoded by the q23-31 region of human chromosome 5. To… 
Highly Cited
1996
Highly Cited
1996
Upregulatory effects of interleukin-4 and interleukin-13 but not interleukin-10 on granulocyte/macrophage colony-stimulating factor production by human bronchial epithelial cells.
Airway epithelial cells are known to produce a granulocyte/macrophage colony-stimulating factor (GM-CSF), which induces… 
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