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IL13-PE38QQR

Known as: IL 13-PE38QQR, IL-13 Toxin, Interleukin-13 PE38QQR Immunotoxin 
A recombinant chimeric protein with potent antitumor activity. Cintredekin besudotox is composed of interleukin-13 (IL13), a pleiotropic… Expand
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Convection-enhanced delivery (CED) of cintredekin besudotox (CB) was compared with Gliadel wafers (GW) in adult patients with… Expand
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Highly Cited
2010
Highly Cited
2010
Restricting the cytotoxicity of anticancer agents by targeting receptors exclusively expressed on tumor cells is critical when… Expand
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Highly Cited
2007
Highly Cited
2007
PURPOSE Glioblastoma multiforme (GBM) is a devastating brain tumor with a median survival of 6 months after recurrence… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVECintredekin besudotox (CB), a recombinant cytotoxin consisting of interleukin-13 and truncated Pseudomonas exotoxin… Expand
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Highly Cited
2007
Highly Cited
2007
OBJECTIVE Convection-enhanced delivery (CED) holds tremendous potential for drug delivery to the brain. However, little is known… Expand
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Highly Cited
2007
Highly Cited
2007
Convection-enhanced delivery (CED) is a novel drug delivery technique that uses positive infusion pressure to deliver therapeutic… Expand
Highly Cited
2005
Highly Cited
2005
OBJECT Convection-enhanced delivery (CED) is a novel method for delivering therapeutic agents to infiltrative brain tumor cells… Expand
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2004
2004
Interstitial infusion of IL13-PE38QQR, a tumor specific, chimeric cytotoxin, into the rat brain stem was performed in an effort… Expand
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Highly Cited
1996
Highly Cited
1996
We have previously shown that human renal cell carcinoma (RCC) cells express large numbers of interleukin-13 receptors (IL-13R… Expand
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